Capsaicin

"Capsaicin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.

Descriptor ID	D002211
MeSH Number(s)	D02.065.160.500 D02.455.326.271.060.222 D02.455.426.559.389.657.166.099 D03.132.760.200 D10.251.355.325.190
Concept/Terms	Capsaicin Capsaicin Capsaicine 8-Methyl-N-Vanillyl-6-Nonenamide 8 Methyl N Vanillyl 6 Nonenamide Antiphlogistine Rub A-535 Capsaicin Antiphlogistine Rub A-535 Capsaicin Axsain Axsain Zacin Capsidol Capsidol Zostrix Zostrix Capzasin Capzasin Gelcen Gelcen Katrum Katrum NGX-4010 NGX-4010 NGX 4010 NGX4010 Capsicum Farmaya Capsicum Farmaya Capsin Capsin

Below are MeSH descriptors whose meaning is more general than "Capsaicin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amides [D02.065]
Polyunsaturated Alkamides [D02.065.160]
Capsaicin [D02.065.160.500]
Hydrocarbons [D02.455]
Hydrocarbons, Acyclic [D02.455.326]
Alkenes [D02.455.326.271]
Polyunsaturated Alkamides [D02.455.326.271.060]
Capsaicin [D02.455.326.271.060.222]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Aromatic [D02.455.426.559]
Benzene Derivatives [D02.455.426.559.389]
Phenols [D02.455.426.559.389.657]
Catechols [D02.455.426.559.389.657.166]
Capsaicin [D02.455.426.559.389.657.166.099]
Heterocyclic Compounds [D03]
Alkaloids [D03.132]
Solanaceous Alkaloids [D03.132.760]
Capsaicin [D03.132.760.200]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Fatty Acids, Monounsaturated [D10.251.355.325]
Capsaicin [D10.251.355.325.190]

Below are MeSH descriptors whose meaning is more specific than "Capsaicin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Capsaicin" by people in this website by year, and whether "Capsaicin" was a major or minor topic of these publications.

Bar chart showing 13 publications over 10 distinct years, with a maximum of 2 publications in 2011 and 2017 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2006	0	1	1
2007	0	1	1
2011	1	1	2
2013	1	0	1
2017	1	1	2
2020	0	1	1
2022	0	1	1
2023	1	1	2
2025	1	0	1

Below are the most recent publications written about "Capsaicin" by people in Profiles.

Hsu J, Kashyap S, Hurd C, McCormack L, Herrmann Z, Schwartz AC, Jackson J, DeMoss D. Treatment of cannabinoid hyperemesis syndrome: A systematic review and treatment algorithm for consultation-liaison psychiatrists. Gen Hosp Psychiatry. 2025 Nov-Dec; 97:185-191.

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Murphy LM, Whelan AR, Griffin LB, Hamel MS. A pilot randomized control trial of topical capsaicin as adjunctive therapy for nausea and vomiting of pregnancy. Am J Obstet Gynecol MFM. 2023 07; 5(7):100997.

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He J, Wu X, Xie Y, Gao Y, McClements DJ, Zhang L, Zou L, Liu W. Capsaicin encapsulated in W/O/W double emulsions fabricated via ethanol-induced pectin gelling: Improvement of bioaccessibility and reduction of irritation. Int J Biol Macromol. 2023 Apr 30; 235:123899.

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Richard MJ, Driban JB, McAlindon TE. Pharmaceutical treatment of osteoarthritis. Osteoarthritis Cartilage. 2023 04; 31(4):458-466.

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Wang J, Sun BL, Xiang Y, Tian DY, Zhu C, Li WW, Liu YH, Bu XL, Shen LL, Jin WS, Wang Z, Zeng GH, Xu W, Chen LY, Chen XW, Hu Z, Zhu ZM, Song W, Zhou HD, Yu JT, Wang YJ. Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice. Transl Psychiatry. 2020 07 13; 10(1):230.

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Hafez Z, Mullins ME, Blohm E, O'Connor MJ, Dezieck L, Schwarz ES, Conicella A. Cannabinoid hyperemesis syndrome and topical capsaicin: treating smoke with fire? - the authors reply. Clin Toxicol (Phila). 2018 01; 56(1):79.

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Dezieck L, Hafez Z, Conicella A, Blohm E, O'Connor MJ, Schwarz ES, Mullins ME. Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Clin Toxicol (Phila). 2017 Sep; 55(8):908-913.

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Zuo GF, Li MH, Zhang JX, Li B, Wang ZM, Wang Q, Xiao H, Chen SL. Capsazepine concentration dependently inhibits currents in HEK 293 cells mediated by human hyperpolarization-activated cyclic nucleotide-gated 2 and 4 channels. Exp Biol Med (Maywood). 2013 Sep; 238(9):1055-61.

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Clausen T, Nielsen OB, Clausen JD, Pedersen TH, Hayward LJ. Na+,K+-pump stimulation improves contractility in isolated muscles of mice with hyperkalemic periodic paralysis. J Gen Physiol. 2011 Jul; 138(1):117-30.

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Luqman S, Meena A, Marler LE, Kondratyuk TP, Pezzuto JM. Suppression of tumor necrosis factor-a-induced nuclear factor ?B activation and aromatase activity by capsaicin and its analog capsazepine. J Med Food. 2011 Nov; 14(11):1344-51.

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