Long Interspersed Nucleotide Elements

"Long Interspersed Nucleotide Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.

Descriptor ID	D020084
MeSH Number(s)	G02.111.570.080.708.330.800.400 G05.360.080.708.330.800.400 G05.360.340.024.425.800.400
Concept/Terms	Long Interspersed Nucleotide Elements Long Interspersed Nucleotide Elements LINE Repeat Sequences LINE Repeat Sequence Repeat Sequence, LINE Repeat Sequences, LINE Sequence, LINE Repeat Sequences, LINE Repeat Long Interspersed DNA Sequence Elements LINE-1 Elements LINE-1 Elements Element, LINE-1 Elements, LINE-1 LINE 1 Elements LINE-1 Element L1 Elements Element, L1 Elements, L1 L1 Element Jockey Elements Jockey Elements Element, Jockey Elements, Jockey Jockey Element

Below are MeSH descriptors whose meaning is more general than "Long Interspersed Nucleotide Elements".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Base Sequence [G02.111.570.080]
Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
Interspersed Repetitive Sequences [G02.111.570.080.708.330]
Retroelements [G02.111.570.080.708.330.800]
Long Interspersed Nucleotide Elements [G02.111.570.080.708.330.800.400]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Base Sequence [G05.360.080]
Repetitive Sequences, Nucleic Acid [G05.360.080.708]
Interspersed Repetitive Sequences [G05.360.080.708.330]
Retroelements [G05.360.080.708.330.800]
Long Interspersed Nucleotide Elements [G05.360.080.708.330.800.400]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Interspersed Repetitive Sequences [G05.360.340.024.425]
Retroelements [G05.360.340.024.425.800]
Long Interspersed Nucleotide Elements [G05.360.340.024.425.800.400]

Below are MeSH descriptors whose meaning is related to "Long Interspersed Nucleotide Elements".

Below are MeSH descriptors whose meaning is more specific than "Long Interspersed Nucleotide Elements".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Long Interspersed Nucleotide Elements" by people in this website by year, and whether "Long Interspersed Nucleotide Elements" was a major or minor topic of these publications.

Bar chart showing 14 publications over 11 distinct years, with a maximum of 2 publications in 2011 and 2014 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	0	1	1
2006	0	1	1
2011	0	2	2
2014	0	2	2
2016	1	0	1
2017	2	0	2
2019	1	0	1
2021	1	0	1
2022	1	0	1
2023	0	1	1

Below are the most recent publications written about "Long Interspersed Nucleotide Elements" by people in Profiles.

Osmanski AB, Paulat NS, Korstian J, Grimshaw JR, Halsey M, Sullivan KAM, Moreno-Santill?n DD, Crookshanks C, Roberts J, Garcia C, Johnson MG, Densmore LD, Stevens RD, Rosen J, Storer JM, Hubley R, Smit AFA, D?valos LM, Karlsson EK, Lindblad-Toh K, Ray DA. Insights into mammalian TE diversity through the curation of 248 genome assemblies. Science. 2023 04 28; 380(6643):eabn1430.

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Creamer KM, Larsen EC, Lawrence JB. ZNF146/OZF and ZNF507 target LINE-1 sequences. G3 (Bethesda). 2022 03 04; 12(3).

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Protasova MS, Andreeva TV, Rogaev EI. Factors Regulating the Activity of LINE1 Retrotransposons. Genes (Basel). 2021 09 30; 12(10).

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Rozek LS, Virani S, Bellile EL, Taylor JMG, Sartor MA, Zarins KR, Virani A, Cote C, Worden FP, Mark MEP, McLean SA, Duffy SA, Yoo GH, Saba NF, Shin DM, Kucuk O, Wolf GT. Soy Isoflavone Supplementation Increases Long Interspersed Nucleotide Element-1 (LINE-1) Methylation in Head and Neck Squamous Cell Carcinoma. Nutr Cancer. 2019; 71(5):772-780.

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Jachowicz JW, Bing X, Pontabry J, Bo?kovic A, Rando OJ, Torres-Padilla ME. LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. Nat Genet. 2017 Oct; 49(10):1502-1510.

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Protasova MS, Gusev FE, Grigorenko AP, Kuznetsova IL, Rogaev EI, Andreeva TV. Quantitative Analysis of L1-Retrotransposons in Alzheimer's Disease and Aging. Biochemistry (Mosc). 2017 Aug; 82(8):962-971.

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Motzek A, Kne?evic J, Switzeny OJ, Cooper A, Baric I, Beluzic R, Strauss KA, Puffenberger EG, Mudd SH, Vugrek O, Zechner U. Abnormal Hypermethylation at Imprinting Control Regions in Patients with S-Adenosylhomocysteine Hydrolase (AHCY) Deficiency. PLoS One. 2016; 11(3):e0151261.

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Sturgeon SR, Arcaro KF, Johnson MA, Balasubramanian R, Zorn M, Jerry DJ, Schneider SS. DNA methylation in paired breast epithelial and white blood cells from women undergoing reduction mammoplasty. Anticancer Res. 2014 Jun; 34(6):2985-90.

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Hall LL, Carone DM, Gomez AV, Kolpa HJ, Byron M, Mehta N, Fackelmayer FO, Lawrence JB. Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes. Cell. 2014 Feb 27; 156(5):907-19.

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Wernimont SM, Clark AG, Stover PJ, Wells MT, Litonjua AA, Weiss ST, Gaziano JM, Tucker KL, Baccarelli A, Schwartz J, Bollati V, Cassano PA. Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study. BMC Med Genet. 2011 Nov 21; 12:150.

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