Regulatory Factor X Transcription Factors
"Regulatory Factor X Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.
| Descriptor ID |
D000071701
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| MeSH Number(s) |
D12.776.260.950.624 D12.776.930.977.624
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Regulatory Factor X Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Regulatory Factor X Transcription Factors".
This graph shows the total number of publications written about "Regulatory Factor X Transcription Factors" by people in this website by year, and whether "Regulatory Factor X Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "Regulatory Factor X Transcription Factors" by people in Profiles.
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Moore BD, Jin RU, Lo H, Jung M, Wang H, Battle MA, Wollheim CB, Urano F, Mills JC. Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4a (HNF4?) Is Vital to Beta-cell Function. J Biol Chem. 2016 Mar 18; 291(12):6146-57.
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Bronner DN, Abuaita BH, Chen X, Fitzgerald KA, Nu?ez G, He Y, Yin XM, O'Riordan MX. Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage. Immunity. 2015 Sep 15; 43(3):451-62.
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Lamech LT, Haynes CM. The unpredictability of prolonged activation of stress response pathways. J Cell Biol. 2015 Jun 22; 209(6):781-7.
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Wallingford MC, Filkins R, Adams D, Walentuk M, Salicioni AM, Visconti PE, Mager J. Identification of a novel isoform of the leukemia-associated MLLT1 (ENL/LTG19) protein. Gene Expr Patterns. 2015 Jan; 17(1):11-5.
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Hua Y, White-Gilbertson S, Kellner J, Rachidi S, Usmani SZ, Chiosis G, Depinho R, Li Z, Liu B. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res. 2013 Nov 15; 19(22):6242-51.
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Tohmonda T, Yoda M, Mizuochi H, Morioka H, Matsumoto M, Urano F, Toyama Y, Horiuchi K. The IRE1a-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis. J Biol Chem. 2013 Jan 18; 288(3):1691-5.
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Tohmonda T, Miyauchi Y, Ghosh R, Yoda M, Uchikawa S, Takito J, Morioka H, Nakamura M, Iwawaki T, Chiba K, Toyama Y, Urano F, Horiuchi K. The IRE1a-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix. EMBO Rep. 2011 May; 12(5):451-7.
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Burkart A, Shi X, Chouinard M, Corvera S. Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response. J Biol Chem. 2011 Feb 11; 286(6):4081-9.
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Ghosh R, Lipson KL, Sargent KE, Mercurio AM, Hunt JS, Ron D, Urano F. Transcriptional regulation of VEGF-A by the unfolded protein response pathway. PLoS One. 2010 Mar 08; 5(3):e9575.
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Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev. 2009 Oct 01; 23(19):2294-306.