X-Box Binding Protein 1

"X-Box Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.

Descriptor ID	D000071717
MeSH Number(s)	D12.776.260.108.937 D12.776.930.127.937
Concept/Terms	X-Box Binding Protein 1 X-Box Binding Protein 1 X Box Binding Protein 1 TREB5 Protein Tax-Responsive Element-Binding Protein 5 Tax Responsive Element Binding Protein 5 XBP-1 Protein XBP 1 Protein TREB-5 Protein TREB 5 Protein XBP2 Protein

Below are MeSH descriptors whose meaning is more general than "X-Box Binding Protein 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
X-Box Binding Protein 1 [D12.776.260.108.937]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
X-Box Binding Protein 1 [D12.776.930.127.937]

Below are MeSH descriptors whose meaning is related to "X-Box Binding Protein 1".

Below are MeSH descriptors whose meaning is more specific than "X-Box Binding Protein 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "X-Box Binding Protein 1" by people in this website by year, and whether "X-Box Binding Protein 1" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2001 and 2008 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	2	2
2006	0	1	1
2008	0	2	2
2009	0	1	1
2010	0	2	2
2011	0	1	1
2013	0	1	1
2018	0	1	1
2024	1	0	1

Below are the most recent publications written about "X-Box Binding Protein 1" by people in Profiles.

Fu Q, Wang Y, Qin J, Xie D, McNally D, Yoon S. Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells. Appl Microbiol Biotechnol. 2024 Sep 04; 108(1):459.

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Sharma RB, Darko C, Alonso LC. Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells. J Biol Chem. 2020 10 09; 295(41):14164-14177.

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Muralidharan S, Lim A, Catalano D, Mandrekar P. Human Binge Alcohol Intake Inhibits TLR4-MyD88 and TLR4-TRIF Responses but Not the TLR3-TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles. J Immunol. 2018 04 01; 200(7):2291-2303.

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Valderrama C, Clark A, Urano F, Unanue ER, Carrero JA. Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice. Eur J Immunol. 2017 05; 47(5):830-840.

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Moore BD, Jin RU, Lo H, Jung M, Wang H, Battle MA, Wollheim CB, Urano F, Mills JC. Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4a (HNF4?) Is Vital to Beta-cell Function. J Biol Chem. 2016 Mar 18; 291(12):6146-57.

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Hua Y, White-Gilbertson S, Kellner J, Rachidi S, Usmani SZ, Chiosis G, Depinho R, Li Z, Liu B. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res. 2013 Nov 15; 19(22):6242-51.

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Tohmonda T, Yoda M, Mizuochi H, Morioka H, Matsumoto M, Urano F, Toyama Y, Horiuchi K. The IRE1a-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis. J Biol Chem. 2013 Jan 18; 288(3):1691-5.

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Lee J, Sun C, Zhou Y, Lee J, Gokalp D, Herrema H, Park SW, Davis RJ, Ozcan U. p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis. Nat Med. 2011 Sep 04; 17(10):1251-60.

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Tohmonda T, Miyauchi Y, Ghosh R, Yoda M, Uchikawa S, Takito J, Morioka H, Nakamura M, Iwawaki T, Chiba K, Toyama Y, Urano F, Horiuchi K. The IRE1a-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix. EMBO Rep. 2011 May; 12(5):451-7.

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Burkart A, Shi X, Chouinard M, Corvera S. Adenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response. J Biol Chem. 2011 Feb 11; 286(6):4081-9.

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