Zinc Finger E-box-Binding Homeobox 1
"Zinc Finger E-box-Binding Homeobox 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.
| Descriptor ID |
D000071799
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| MeSH Number(s) |
D12.776.260.400.906 D12.776.260.703.800 D12.776.930.780.945
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| Concept/Terms |
Zinc Finger E-box-Binding Homeobox 1- Zinc Finger E-box-Binding Homeobox 1
- Zinc Finger E box Binding Homeobox 1
- NIL-2-A Zinc Finger Protein
- NIL 2 A Zinc Finger Protein
- TCF8 Protein
- Zeb1 Transcription Factor
- Transcription Factor, Zeb1
- Transcription Factor 8
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Below are MeSH descriptors whose meaning is more general than "Zinc Finger E-box-Binding Homeobox 1".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger E-box-Binding Homeobox 1".
This graph shows the total number of publications written about "Zinc Finger E-box-Binding Homeobox 1" by people in this website by year, and whether "Zinc Finger E-box-Binding Homeobox 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Zinc Finger E-box-Binding Homeobox 1" by people in Profiles.
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Goel HL, Karner ER, Kumar A, Mukhopadhyay D, Goel S, Mercurio AM. YAP/TAZ-mediated regulation of laminin 332 is enabled by ?4 integrin repression of ZEB1 to promote ferroptosis resistance. J Biol Chem. 2024 04; 300(4):107202.
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Vincent-Mistiaen Z, Elbediwy A, Vanyai H, Cotton J, Stamp G, Nye E, Spencer-Dene B, Thomas GJ, Mao J, Thompson B. YAP drives cutaneous squamous cell carcinoma formation and progression. Elife. 2018 09 20; 7.
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Hong D, Fritz AJ, Finstad KH, Fitzgerald MP, Weinheimer A, Viens AL, Ramsey J, Stein JL, Lian JB, Stein GS. Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor. Mol Cancer Res. 2018 12; 16(12):1952-1964.
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Chao CH, Chang CC, Wu MJ, Ko HW, Wang D, Hung MC, Yang JY, Chang CJ. MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. J Clin Invest. 2014 Jul; 124(7):3093-106.
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Yen G, Croci A, Dowling A, Zhang S, Zoeller RT, Darling DS. Developmental and functional evidence of a role for Zfhep in neural cell development. Brain Res Mol Brain Res. 2001 Nov 30; 96(1-2):59-67.