IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.
Nishihara M, Ogura H, Ueda N, Tsuruoka M, Kitabayashi C, Tsuji F, Aono H, Ishihara K, Huseby E, Betz UA, Murakami M, Hirano T. IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state. Int Immunol. 2007 Jun; 19(6):695-702.
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Animals
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Arthritis, Experimental
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CD4-Positive T-Lymphocytes
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Cell Count
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Cell Differentiation
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Cytokine Receptor gp130
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Flow Cytometry
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Forkhead Transcription Factors
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Interleukin-17
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Interleukin-6
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Lymph Nodes
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Lymphocyte Activation
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Mice
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Mice, Inbred C57BL
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Mice, Inbred DBA
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Mice, Knockout
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Mice, Transgenic
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Nuclear Receptor Subfamily 1, Group F, Member 3
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Receptors, Retinoic Acid
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Receptors, Thyroid Hormone
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Signal Transduction
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Spleen
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STAT3 Transcription Factor
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T-Lymphocytes, Helper-Inducer
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T-Lymphocytes, Regulatory