Tetrahydrobiopterin, L-arginine and vitamin C actsynergistically to decrease oxidative stress, increase nitricoxide and improve blood flow after induction of hindlimbischemia in the rat.

Yan J, Tie G, Messina LM. Tetrahydrobiopterin, L-arginine and vitamin C actsynergistically to decrease oxidative stress, increase nitricoxide and improve blood flow after induction of hindlimbischemia in the rat. Mol Med. 2012 May 09; 18:676-84.

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subject areas

Administration, Oral
Animals
Antioxidants
Arginine
Ascorbic Acid
Calcium
Drug Synergism
Enzyme Activation
Hindlimb
Ischemia
Male
Muscle, Skeletal
Necrosis
Nitric Oxide
Nitric Oxide Synthase Type III
Oxidative Stress
Rats
Rats, Sprague-Dawley
Regional Blood Flow

authors with profiles

Louis M Messina MD