Receptors, Platelet-Derived Growth Factor
"Receptors, Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
| Descriptor ID |
D017479
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900 D12.776.543.750.630.625 D12.776.543.750.750.400.630
|
| Concept/Terms |
Receptors, Platelet-Derived Growth Factor- Receptors, Platelet-Derived Growth Factor
- Receptors, Platelet Derived Growth Factor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- Receptors, PDGF
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Receptors, Platelet-Derived Growth Factor" by people in this website by year, and whether "Receptors, Platelet-Derived Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Platelet-Derived Growth Factor" by people in Profiles.
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Tracy JC, Klement GL, Scott AR. Interdisciplinary management of congenital infiltrating lipomatosis. Int J Pediatr Otorhinolaryngol. 2013 Dec; 77(12):2071-4.
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Velez G, Weingarden AR, Lei H, Kazlauskas A, Gao G. SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified M?ller cell-induced rabbit models. Invest Ophthalmol Vis Sci. 2013 Feb 19; 54(2):1392-7.
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Lei H, Velez G, Hovland P, Hirose T, Kazlauskas A. Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):42-8.
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Chen K, Thomas SR, Albano A, Murphy MP, Keaney JF. Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling. J Biol Chem. 2004 Aug 13; 279(33):35079-86.
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Weinman EJ, Lakkis J, Akom M, Wali RK, Drachenberg CB, Coleman RA, Wade JB. Expression of NHERF-1, NHERF-2, PDGFR-alpha, and PDGFR-beta in normal human kidneys and in renal transplant rejection. Pathobiology. 2002-2003; 70(6):314-23.
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Shpetner H, Joly M, Hartley D, Corvera S. Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J Cell Biol. 1996 Feb; 132(4):595-605.
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Joly M, Kazlauskas A, Corvera S. Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J Biol Chem. 1995 Jun 02; 270(22):13225-30.
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Joly M, Kazlauskas A, Fay FS, Corvera S. Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science. 1994 Feb 04; 263(5147):684-7.
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Kapeller R, Chakrabarti R, Cantley L, Fay F, Corvera S. Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton. Mol Cell Biol. 1993 Oct; 13(10):6052-63.