Nicotinamide-Nucleotide Adenylyltransferase
"Nicotinamide-Nucleotide Adenylyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals.
| Descriptor ID |
D009612
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| MeSH Number(s) |
D08.811.913.696.445.600 D12.776.157.687.499 D12.776.660.720.499
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| Concept/Terms |
Nicotinamide-Nucleotide Adenylyltransferase- Nicotinamide-Nucleotide Adenylyltransferase
- Adenylyltransferase, Nicotinamide-Nucleotide
- Nicotinamide Nucleotide Adenylyltransferase
- NMN Adenylyltransferase
- Adenylyltransferase, NMN
- Nicotinamide Mononucleotide Adenylyltransferase
- Adenylyltransferase, Nicotinamide Mononucleotide
- Mononucleotide Adenylyltransferase, Nicotinamide
- ATP-NMN Adenylyltransferase
- ATP NMN Adenylyltransferase
- Adenylyltransferase, ATP-NMN
- NAD Pyrophosphorylase
- Pyrophosphorylase, NAD
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Below are MeSH descriptors whose meaning is more general than "Nicotinamide-Nucleotide Adenylyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Nicotinamide-Nucleotide Adenylyltransferase".
This graph shows the total number of publications written about "Nicotinamide-Nucleotide Adenylyltransferase" by people in this website by year, and whether "Nicotinamide-Nucleotide Adenylyltransferase" was a major or minor topic of these publications.
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Below are the most recent publications written about "Nicotinamide-Nucleotide Adenylyltransferase" by people in Profiles.
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Neukomm LJ, Burdett TC, Seeds AM, Hampel S, Coutinho-Budd JC, Farley JE, Wong J, Karadeniz YB, Osterloh JM, Sheehan AE, Freeman MR. Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly. Neuron. 2017 Jul 05; 95(1):78-91.e5.
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Milde S, Fox AN, Freeman MR, Coleman MP. Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo. Sci Rep. 2013; 3:2567.
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Avery MA, Rooney TM, Pandya JD, Wishart TM, Gillingwater TH, Geddes JW, Sullivan PG, Freeman MR. WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Curr Biol. 2012 Apr 10; 22(7):596-600.
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Coleman MP, Freeman MR. Wallerian degeneration, wld(s), and nmnat. Annu Rev Neurosci. 2010; 33:245-67.
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Avery MA, Sheehan AE, Kerr KS, Wang J, Freeman MR. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. J Cell Biol. 2009 Feb 23; 184(4):501-13.