Prostaglandin-Endoperoxide Synthases

"Prostaglandin-Endoperoxide Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzyme complexes that catalyze the formation of PROSTAGLANDINS from the appropriate unsaturated FATTY ACIDS, molecular OXYGEN, and a reduced acceptor.

Descriptor ID	D011451
MeSH Number(s)	D08.811.600.720 D08.811.682.690.708.715
Concept/Terms	Prostaglandin-Endoperoxide Synthases Prostaglandin-Endoperoxide Synthases Prostaglandin Endoperoxide Synthases Synthases, Prostaglandin-Endoperoxide Prostaglandin-Endoperoxide Synthase Synthase, Prostaglandin-Endoperoxide Cyclooxygenase Cyclooxygenases Fatty Acid Cyclo-Oxygenase Cyclo-Oxygenase, Fatty Acid Fatty Acid Cyclo Oxygenase Hydroperoxide Cyclase Cyclase, Hydroperoxide PGH Synthase Synthase, PGH PGH2 Synthetase Synthetase, PGH2 Prostaglandin Cyclo-Oxygenase Cyclo-Oxygenase, Prostaglandin Prostaglandin Cyclo Oxygenase Prostaglandin Cyclooxygenase Cyclooxygenase, Prostaglandin Prostaglandin Endoperoxide Synthetase Endoperoxide Synthetase, Prostaglandin Synthetase, Prostaglandin Endoperoxide Prostaglandin G-H Synthase G-H Synthase, Prostaglandin Prostaglandin G H Synthase Synthase, Prostaglandin G-H Prostaglandin H Synthase Synthase, Prostaglandin H Prostaglandin H2 Synthetase Synthetase, Prostaglandin H2 Prostaglandin Synthase Synthase, Prostaglandin Prostaglandin Synthetase Synthetase, Prostaglandin Arachidonic Acid Cyclooxygenase Cyclooxygenase, Arachidonic Acid Cyclo-Oxygenase Cyclo Oxygenase

Below are MeSH descriptors whose meaning is more general than "Prostaglandin-Endoperoxide Synthases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Multienzyme Complexes [D08.811.600]
Prostaglandin-Endoperoxide Synthases [D08.811.600.720]
Oxidoreductases [D08.811.682]
Oxygenases [D08.811.682.690]
Mixed Function Oxygenases [D08.811.682.690.708]
Prostaglandin-Endoperoxide Synthases [D08.811.682.690.708.715]

Below are MeSH descriptors whose meaning is related to "Prostaglandin-Endoperoxide Synthases".

Below are MeSH descriptors whose meaning is more specific than "Prostaglandin-Endoperoxide Synthases".

Prostaglandin-Endoperoxide Synthases
Cyclooxygenase 1
Cyclooxygenase 2

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Prostaglandin-Endoperoxide Synthases" by people in this website by year, and whether "Prostaglandin-Endoperoxide Synthases" was a major or minor topic of these publications.

Bar chart showing 30 publications over 9 distinct years, with a maximum of 10 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	0	1
1998	0	1	1
2000	1	1	2
2001	1	0	1
2002	2	6	8
2003	0	2	2
2004	3	7	10
2005	1	3	4

Below are the most recent publications written about "Prostaglandin-Endoperoxide Synthases" by people in Profiles.

Shea-Donohue T, Notari L, Stiltz J, Sun R, Madden KB, Urban JF, Zhao A. Role of enteric nerves in immune-mediated changes in protease-activated receptor 2 effects on gut function. Neurogastroenterol Motil. 2010 Oct; 22(10):1138-e291.

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Youn HS, Lee JY, Fitzgerald KA, Young HA, Akira S, Hwang DH. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J Immunol. 2005 Sep 01; 175(5):3339-46.

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Laouini D, Elkhal A, Yalcindag A, Kawamoto S, Oettgen H, Geha RS. COX-2 inhibition enhances the TH2 immune response to epicutaneous sensitization. J Allergy Clin Immunol. 2005 Aug; 116(2):390-6.

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Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain. 2005 Jun; 128(Pt 6):1442-53.

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Grall FT, Prall WC, Wei W, Gu X, Cho JY, Choy BK, Zerbini LF, Inan MS, Goldring SR, Gravallese EM, Goldring MB, Oettgen P, Libermann TA. The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes. FEBS J. 2005 Apr; 272(7):1676-87.

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Stebulis JA, Rossetti RG, Atez FJ, Zurier RB. Fibroblast-like synovial cells derived from synovial fluid. J Rheumatol. 2005 Feb; 32(2):301-6.

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Su BN, Jones WP, Cuendet M, Kardono LB, Ismail R, Riswan S, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemistry. 2004 Nov; 65(21):2861-6.

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Gafner S, Lee SK, Cuendet M, Barth?l?my S, Vergnes L, Labidalle S, Mehta RG, Boone CW, Pezzuto JM. Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems. Phytochemistry. 2004 Nov; 65(21):2849-59.

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Jang DS, Cuendet M, Su BN, Totura S, Riswan S, Fong HH, Pezzuto JM, Kinghorn AD. Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2. Planta Med. 2004 Oct; 70(10):893-6.

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Scarpa RC, Carraway RE, Cochrane DE. The effect of neurotensin on insulin-induced proliferation of human fibroblasts. Peptides. 2004 Jul; 25(7):1159-69.

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