"Utrophin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to DYSTROPHIN. It is a ubiquitously-expressed protein that plays a role in anchoring the CYTOSKELETON to the PLASMA MEMBRANE.
| Descriptor ID |
D049411
|
| MeSH Number(s) |
D12.776.220.987 D12.776.543.985
|
| Concept/Terms |
Utrophin- Utrophin
- UTRN Protein
- Dystrophin-Related Protein
- Dystrophin Related Protein
- Dystrophin-Related Protein 1
- Dystrophin Related Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Utrophin".
Below are MeSH descriptors whose meaning is more specific than "Utrophin".
This graph shows the total number of publications written about "Utrophin" by people in this website by year, and whether "Utrophin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Utrophin" by people in Profiles.
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Hart CC, Lee YI, Xie J, Gao G, Lin BL, Hammers DW, Sweeney HL. Potential limitations of microdystrophin gene therapy for Duchenne muscular dystrophy. JCI Insight. 2024 May 07; 9(11).
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Lehman W, Craig R, Kendrick-Jones J, Sutherland-Smith AJ. An open or closed case for the conformation of calponin homology domains on F-actin? J Muscle Res Cell Motil. 2004; 25(4-5):351-8.
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Gyrd-Hansen M, Krag TO, Rosmarin AG, Khurana TS. Sp1 and the ets-related transcription factor complex GABP alpha/beta functionally cooperate to activate the utrophin promoter. J Neurol Sci. 2002 May 15; 197(1-2):27-35.
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Khurana TS, Rosmarin AG, Shang J, Krag TO, Das S, Gammeltoft S. Activation of utrophin promoter by heregulin via the ets-related transcription factor complex GA-binding protein alpha/beta. Mol Biol Cell. 1999 Jun; 10(6):2075-86.