Receptors, Interleukin-2

"Receptors, Interleukin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Receptors present on activated T-LYMPHOCYTES and B-LYMPHOCYTES that are specific for INTERLEUKIN-2 and play an important role in LYMPHOCYTE ACTIVATION. They are heterotrimeric proteins consisting of the INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN.

Descriptor ID	D015375
MeSH Number(s)	D12.776.543.750.705.852.420.320
Concept/Terms	Receptors, Interleukin-2 Receptors, Interleukin-2 Receptors, Interleukin 2 TCGF Receptor TCGF Receptors Receptors, TCGF IL-2 Receptor IL 2 Receptor Receptor, IL-2 IL-2 Receptors IL 2 Receptors T-Cell Growth Factor Receptor T Cell Growth Factor Receptor IL2 Receptors Receptors, IL2 Interleukin 2 Receptor Receptor, Interleukin 2 Interleukin-2 Receptors Interleukin 2 Receptors Receptor, TCGF Receptors, IL-2 Receptors, IL 2 Receptors, T-Cell Growth Factor Receptors, T Cell Growth Factor T-Cell Growth Factor Receptors T Cell Growth Factor Receptors IL2 Receptor Receptor, IL2

Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-2 [D12.776.543.750.705.852.420.320]

Below are MeSH descriptors whose meaning is related to "Receptors, Interleukin-2".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-2".

Receptors, Interleukin-2
Interleukin Receptor Common gamma Subunit
Interleukin-2 Receptor alpha Subunit
Interleukin-2 Receptor beta Subunit

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Interleukin-2" by people in this website by year, and whether "Receptors, Interleukin-2" was a major or minor topic of these publications.

Bar chart showing 40 publications over 17 distinct years, with a maximum of 8 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	3	3
1998	0	2	2
1999	0	1	1
2001	0	1	1
2002	0	1	1
2003	4	4	8
2004	3	2	5
2005	2	3	5
2006	0	1	1
2007	2	0	2
2008	0	2	2
2010	2	0	2
2011	2	0	2
2012	0	1	1
2014	0	1	1
2015	1	1	2

Below are the most recent publications written about "Receptors, Interleukin-2" by people in Profiles.

Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV. The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. J Immunol. 2015 Oct 01; 195(7):3011-9.

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Babad J, Mukherjee G, Follenzi A, Ali R, Roep BO, Shultz LD, Santamaria P, Yang OO, Goldstein H, Greiner DL, DiLorenzo TP. Generation of ? cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice. Clin Exp Immunol. 2015 Mar; 179(3):398-413.

View in: PubMed
Brehm MA, Wiles MV, Greiner DL, Shultz LD. Generation of improved humanized mouse models for human infectious diseases. J Immunol Methods. 2014 Aug; 410:3-17.

View in: PubMed
Brehm MA, Powers AC, Shultz LD, Greiner DL. Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med. 2012 May; 2(5):a007757.

View in: PubMed
Covassin L, Laning J, Abdi R, Langevin DL, Phillips NE, Shultz LD, Brehm MA. Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2r?(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease. Clin Exp Immunol. 2011 Nov; 166(2):269-80.

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Gabardi S, Catella J, Martin ST, Perrone R, Chandraker A, Magee CC, McDevitt-Potter LM. Maintenance immunosuppression with intermittent intravenous IL-2 receptor antibody therapy in renal transplant recipients. Ann Pharmacother. 2011 Sep; 45(9):e48.

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Racki WJ, Covassin L, Brehm M, Pino S, Ignotz R, Dunn R, Laning J, Graves SK, Rossini AA, Shultz LD, Greiner DL. NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation. 2010 Mar 15; 89(5):527-36.

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Pino S, Brehm MA, Covassin-Barberis L, King M, Gott B, Chase TH, Wagner J, Burzenski L, Foreman O, Greiner DL, Shultz LD. Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. Methods Mol Biol. 2010; 602:105-17.

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Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL. A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function. Diabetologia. 2008 Aug; 51(8):1449-56.

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Simpson-Abelson MR, Sonnenberg GF, Takita H, Yokota SJ, Conway TF, Kelleher RJ, Shultz LD, Barcos M, Bankert RB. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice. J Immunol. 2008 May 15; 180(10):7009-18.

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