Genetic Fitness

"Genetic Fitness" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The capability of an organism to survive and reproduce. The phenotypic expression of the genotype in a particular environment determines how genetically fit an organism will be.

Descriptor ID	D056084
MeSH Number(s)	G05.347
Concept/Terms	Genetic Fitness Genetic Fitness Fitness, Genetic Darwinian Fitness Darwinian Fitness Fitness, Darwinian Reproductive Fitness Reproductive Fitness Fitness, Reproductive

Below are MeSH descriptors whose meaning is more general than "Genetic Fitness".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Fitness [G05.347]

Below are MeSH descriptors whose meaning is related to "Genetic Fitness".

Below are MeSH descriptors whose meaning is more specific than "Genetic Fitness".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genetic Fitness" by people in this website by year, and whether "Genetic Fitness" was a major or minor topic of these publications.

Bar chart showing 19 publications over 12 distinct years, with a maximum of 3 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	0	1	1
2011	0	1	1
2012	1	0	1
2013	2	1	3
2014	2	1	3
2016	0	2	2
2017	0	1	1
2018	2	0	2
2020	0	1	1
2021	2	0	2
2022	1	0	1
2023	1	0	1

Below are the most recent publications written about "Genetic Fitness" by people in Profiles.

Flynn J, Samant N, Schneider-Nachum G, Tenzin T, Bolon DNA. Mutational fitness landscape and drug resistance. Curr Opin Struct Biol. 2023 02; 78:102525.

View in: PubMed
Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. Science. 2022 06 17; 376(6599):1327-1332.

View in: PubMed
Thomson EC, Rosen LE, Shepherd JG, Spreafico R, da Silva Filipe A, Wojcechowskyj JA, Davis C, Piccoli L, Pascall DJ, Dillen J, Lytras S, Czudnochowski N, Shah R, Meury M, Jesudason N, De Marco A, Li K, Bassi J, O'Toole A, Pinto D, Colquhoun RM, Culap K, Jackson B, Zatta F, Rambaut A, Jaconi S, Sreenu VB, Nix J, Zhang I, Jarrett RF, Glass WG, Beltramello M, Nomikou K, Pizzuto M, Tong L, Cameroni E, Croll TI, Johnson N, Di Iulio J, Wickenhagen A, Ceschi A, Harbison AM, Mair D, Ferrari P, Smollett K, Sallusto F, Carmichael S, Garzoni C, Nichols J, Galli M, Hughes J, Riva A, Ho A, Schiuma M, Semple MG, Openshaw PJM, Fadda E, Baillie JK, Chodera JD, Rihn SJ, Lycett SJ, Virgin HW, Telenti A, Corti D, Robertson DL, Snell G. Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. Cell. 2021 03 04; 184(5):1171-1187.e20.

View in: PubMed
Cote-Hammarlof PA, Fragata I, Flynn J, Mavor D, Zeldovich KB, Bank C, Bolon DNA. The Adaptive Potential of the Middle Domain of Yeast Hsp90. Mol Biol Evol. 2021 01 23; 38(2):368-379.

View in: PubMed
Flynn JM, Rossouw A, Cote-Hammarlof P, Fragata I, Mavor D, Hollins C, Bank C, Bolon DN. Comprehensive fitness maps of Hsp90 show widespread environmental dependence. Elife. 2020 03 04; 9.

View in: PubMed
Canale AS, Venev SV, Whitfield TW, Caffrey DR, Marasco WA, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Zeldovich KB, Wang JP, Bolon DNA. Synonymous Mutations at the Beginning of the Influenza A Virus Hemagglutinin Gene Impact Experimental Fitness. J Mol Biol. 2018 04 13; 430(8):1098-1115.

View in: PubMed
Canale AS, Cote-Hammarlof PA, Flynn JM, Bolon DN. Evolutionary mechanisms studied through protein fitness landscapes. Curr Opin Struct Biol. 2018 02; 48:141-148.

View in: PubMed
Renzette N, Pfeifer SP, Matuszewski S, Kowalik TF, Jensen JD. On the Analysis of Intrahost and Interhost Viral Populations: Human Cytomegalovirus as a Case Study of Pitfalls and Expectations. J Virol. 2017 03 01; 91(5).

View in: PubMed
Mishra P, Flynn JM, Starr TN, Bolon DNA. Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function. Cell Rep. 2016 Apr 19; 15(3):588-598.

View in: PubMed
Boucher JI, Bolon DN, Tawfik DS. Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature. Protein Sci. 2016 07; 25(7):1219-26.

View in: PubMed

People

Explore

Similar Concepts

Top Journals