"Frameshifting, Ribosomal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A directed change in translational READING FRAMES that allows the production of a single protein from two or more OVERLAPPING GENES. The process is programmed by the nucleotide sequence of the MRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in VIRUSES (especially RETROVIRUSES); RETROTRANSPOSONS; and bacterial insertion elements but also in some cellular genes.
| Descriptor ID |
D018965
|
| MeSH Number(s) |
G02.111.660.871.200 G03.734.871.200 G05.308.215
|
| Concept/Terms |
Frameshifting, Ribosomal- Frameshifting, Ribosomal
- Ribosomal Frame Shift
- Frame Shift, Ribosomal
- Frame Shifts, Ribosomal
- Ribosomal Frame Shifts
- Frameshifting, Translational
- Translational Frameshifting
- Ribosomal Frameshifting
- Ribosomal Frameshift
- Frameshift, Ribosomal
- Frameshifts, Ribosomal
- Ribosomal Frameshifts
- Ribosomal Frame Shifting
- Frame Shifting, Ribosomal
|
Below are MeSH descriptors whose meaning is more general than "Frameshifting, Ribosomal".
Below are MeSH descriptors whose meaning is more specific than "Frameshifting, Ribosomal".
This graph shows the total number of publications written about "Frameshifting, Ribosomal" by people in this website by year, and whether "Frameshifting, Ribosomal" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frameshifting, Ribosomal" by people in Profiles.
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Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE, Svidritskiy E, Hou YM, Korostelev AA. Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun. 2021 07 30; 12(1):4644.
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Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N, Ermolenko DN. mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding. Elife. 2020 05 19; 9.
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Gao FB, Richter JD, Cleveland DW. Rethinking Unconventional Translation in Neurodegeneration. Cell. 2017 Nov 16; 171(5):994-1000.
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Ivanov IP, Simin K, Letsou A, Atkins JF, Gesteland RF. The Drosophila gene for antizyme requires ribosomal frameshifting for expression and contains an intronic gene for snRNP Sm D3 on the opposite strand. Mol Cell Biol. 1998 Mar; 18(3):1553-61.