"GRB2 Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS).
Descriptor ID |
D051380
|
MeSH Number(s) |
D12.644.360.024.290 D12.776.157.057.041 D12.776.476.024.377
|
Concept/Terms |
GRB2 Adaptor Protein- GRB2 Adaptor Protein
- Abundant Src Homology Protein
- Growth Factor Receptor-Bound Protein-2
- Growth Factor Receptor Bound Protein 2
|
Below are MeSH descriptors whose meaning is more general than "GRB2 Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "GRB2 Adaptor Protein".
This graph shows the total number of publications written about "GRB2 Adaptor Protein" by people in this website by year, and whether "GRB2 Adaptor Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "GRB2 Adaptor Protein" by people in Profiles.
-
Estrada-Zuniga CM, Cheng ZM, Ethiraj P, Guo Q, Gonzalez-Cant? H, Adderley E, Lopez H, Landry BN, Zainal A, Aronin N, Ding Y, Wang X, Aguiar RCT, Dahia PLM. A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions. Cell Rep Med. 2022 07 19; 3(7):100686.
-
Spector SA, Olson ET, Gumbs AA, Friess H, B?chler MW, Seymour NE. Human insulin receptor and insulin signaling proteins in hepatic disease. J Surg Res. 1999 May 01; 83(1):32-5.
-
Boney CM, Smith RM, Gruppuso PA. Modulation of insulin-like growth factor I mitogenic signaling in 3T3-L1 preadipocyte differentiation. Endocrinology. 1998 Apr; 139(4):1638-44.