DNA

"DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Descriptor ID	D004247
MeSH Number(s)	D13.444.308
Concept/Terms	DNA DNA Deoxyribonucleic Acid DNA, Double-Stranded DNA, Double-Stranded DNA, Double Stranded Double-Stranded DNA ds-DNA ds DNA

Below are MeSH descriptors whose meaning is more general than "DNA".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]

Below are MeSH descriptors whose meaning is related to "DNA".

Below are MeSH descriptors whose meaning is more specific than "DNA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA" by people in this website by year, and whether "DNA" was a major or minor topic of these publications.

Bar chart showing 60 publications over 25 distinct years, with a maximum of 8 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2000	0	1	1
2001	1	1	2
2002	0	1	1
2003	0	4	4
2004	0	1	1
2005	3	0	3
2006	4	1	5
2007	1	1	2
2008	0	3	3
2009	0	2	2
2010	1	2	3
2012	5	3	8
2013	4	0	4
2014	1	1	2
2015	1	1	2
2016	1	1	2
2017	1	1	2
2018	1	1	2
2019	1	1	2
2020	1	0	1
2022	0	2	2
2023	0	2	2
2024	0	2	2

Below are the most recent publications written about "DNA" by people in Profiles.

Bamidele N, Zhang H, Dong X, Cheng H, Gaston N, Feinzig H, Cao H, Kelly K, Watts JK, Xie J, Gao G, Sontheimer EJ. Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope. Nat Commun. 2024 Feb 17; 15(1):1458.

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Ferrer-Diaz AI, Sinha G, Petryna A, Gonzalez-Bermejo R, Kenfack Y, Adetayo O, Patel SA, Hooda-Nehra A, Rameshwar P. Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells. Cell Commun Signal. 2024 02 12; 22(1):119.

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Ahmad MH, Hegde M, Wong WJ, Mohammadhosseini M, Garrett L, Carrascoso A, Issac N, Ebert B, Silva JC, Pihan G, Zhu LJ, Wolfe SA, Agarwal A, Liu PP, Castilla LH. Runx1-R188Q germ line mutation induces inflammation and predisposition to hematologic malignancies in mice. Blood Adv. 2023 12 12; 7(23):7304-7318.

View in: PubMed
Liang SQ, Liu P, Ponnienselvan K, Suresh S, Chen Z, Kramme C, Chatterjee P, Zhu LJ, Sontheimer EJ, Xue W, Wolfe SA. Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. Nat Methods. 2023 Jun; 20(6):898-907.

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Iyer S, Mir A, Vega-Badillo J, Roscoe BP, Ibraheim R, Zhu LJ, Lee J, Liu P, Luk K, Mintzer E, Guo D, Soares de Brito J, Emerson CP, Zamore PD, Sontheimer EJ, Wolfe SA. Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors. CRISPR J. 2022 10; 5(5):685-701.

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Ober-Reynolds B, Becker WR, Jouravleva K, Jolly SM, Zamore PD, Greenleaf WJ. High-throughput biochemical profiling reveals functional adaptation of a bacterial Argonaute. Mol Cell. 2022 04 07; 82(7):1329-1342.e8.

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Liang SQ, Liu P, Smith JL, Mintzer E, Maitland S, Dong X, Yang Q, Lee J, Haynes CM, Zhu LJ, Watts JK, Sontheimer EJ, Wolfe SA, Xue W. Genome-wide detection of CRISPR editing in vivo using GUIDE-tag. Nat Commun. 2022 Jan 21; 13(1):437.

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Keshawarz A, Joehanes R, Guan W, Huan T, DeMeo DL, Grove ML, Fornage M, Levy D, O'Connor G. Longitudinal change in blood DNA epigenetic signature after smoking cessation. Epigenetics. 2022 10; 17(10):1098-1109.

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Sahu B, Chug I, Khanna H. The Ocular Gene Delivery Landscape. Biomolecules. 2021 08 01; 11(8).

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Jolly SM, Gainetdinov I, Jouravleva K, Zhang H, Strittmatter L, Bailey SM, Hendricks GM, Dhabaria A, Ueberheide B, Zamore PD. Thermus thermophilus Argonaute Functions in the Completion of DNA Replication. Cell. 2020 09 17; 182(6):1545-1559.e18.

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