DNA

"DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Descriptor ID	D004247
MeSH Number(s)	D13.444.308
Concept/Terms	DNA DNA Deoxyribonucleic Acid DNA, Double-Stranded DNA, Double-Stranded DNA, Double Stranded Double-Stranded DNA ds-DNA ds DNA

Below are MeSH descriptors whose meaning is more general than "DNA".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]

Below are MeSH descriptors whose meaning is related to "DNA".

Below are MeSH descriptors whose meaning is more specific than "DNA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA" by people in this website by year, and whether "DNA" was a major or minor topic of these publications.

Bar chart showing 561 publications over 31 distinct years, with a maximum of 33 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	14	16
1996	1	7	8
1997	3	4	7
1998	5	6	11
1999	6	4	10
2000	6	6	12
2001	6	10	16
2002	11	16	27
2003	11	14	25
2004	11	14	25
2005	11	16	27
2006	12	13	25
2007	7	12	19
2008	8	16	24
2009	10	13	23
2010	9	14	23
2011	7	10	17
2012	24	9	33
2013	10	13	23
2014	11	9	20
2015	8	8	16
2016	9	13	22
2017	10	5	15
2018	11	11	22
2019	11	4	15
2020	5	5	10
2021	3	10	13
2022	0	18	18
2023	4	19	23
2024	2	13	15
2025	1	0	1

Below are the most recent publications written about "DNA" by people in Profiles.

Mishra N, Mohs M, Wittmann N, Gross S, Thompson PR, Bossaller L. PLC and PAD2 Regulate Extracellular Calcium-Triggered Release of Macrophage Extracellular DNA Traps. Eur J Immunol. 2025 Apr; 55(4):e202350942.

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Seddon JM, De D, Grunenkovaite L, Ferrara D. Clinical and Imaging Characteristics of PRPH2 Retinopathies in a Longitudinal Cohort and Diagnostic Implications. Invest Ophthalmol Vis Sci. 2024 Dec 02; 65(14):31.

View in: PubMed
Greiner-Tollersrud OK, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, Abdullah Z, Andryka-Cegielski K, Dominick FI, Huebscher K, Goschin A, Smulski CR, Trompouki E, Link R, Ebersbach H, Srinivas H, Marchant M, Sogkas G, Staab D, V?gb? C, Guerini D, Baasch S, Latz E, Hartmann G, Henneke P, Geiger R, Peng XP, Grimbacher B, Bartok E, Alseth I, Warncke M, Proietti M. ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA. Cell Rep. 2024 11 26; 43(11):114899.

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Dong M, Fitzgerald KA. DNA-sensing pathways in health, autoinflammatory and autoimmune diseases. Nat Immunol. 2024 Nov; 25(11):2001-2014.

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MalagodaPathiranage K, Banerjee R, Martin CT. A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase. Nucleic Acids Res. 2024 Sep 23; 52(17):10607-10618.

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Conte M, Abraham A, Esposito A, Yang L, Gibcus JH, Parsi KM, Vercellone F, Fontana A, Di Pierno F, Dekker J, Nicodemi M. Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations. Int J Mol Sci. 2024 Sep 23; 25(18).

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Yang XY, Shen Z, Wang C, Nakanishi K, Fu TM. DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell. 2024 Sep 19; 187(19):5253-5266.e16.

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Rhind N. In through the out door: A loop-binding-first model for topological cohesin loading. Bioessays. 2024 Oct; 46(10):e2400120.

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Wu MJ, Kondo H, Kammula AV, Shi L, Xiao Y, Dhiab S, Xu Q, Slater CJ, Avila OI, Merritt J, Kato H, Kattel P, Sussman J, Gritti I, Eccleston J, Sun Y, Cho HM, Olander K, Katsuda T, Shi DD, Savani MR, Smith BC, Cleary JM, Mostoslavsky R, Vijay V, Kitagawa Y, Wakimoto H, Jenkins RW, Yates KB, Paik J, Tassinari A, Saatcioglu DH, Tron AE, Haas W, Cahill D, McBrayer SK, Manguso RT, Bardeesy N. Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity. Science. 2024 07 12; 385(6705):eadl6173.

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Sandler SJ, Bonde NJ, Wood EA, Cox MM, Keck JL. The intrinsically disordered linker in the single-stranded DNA-binding protein influences DNA replication restart and recombination pathways in Escherichia coli K-12. J Bacteriol. 2024 04 18; 206(4):e0033023.

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