Synaptic Transmission

"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.

Descriptor ID	D009435
MeSH Number(s)	G02.111.820.850 G04.835.850 G07.265.880 G11.561.830
Concept/Terms	Synaptic Transmission Synaptic Transmission Neural Transmission Neurotransmission Transmission, Neural Transmission, Synaptic

Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Synaptic Transmission [G02.111.820.850]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Synaptic Transmission [G04.835.850]
Physiological Phenomena [G07]
Electrophysiological Phenomena [G07.265]
Synaptic Transmission [G07.265.880]
Musculoskeletal and Neural Physiological Phenomena [G11]
Nervous System Physiological Phenomena [G11.561]
Synaptic Transmission [G11.561.830]

Below are MeSH descriptors whose meaning is related to "Synaptic Transmission".

Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".

Synaptic Transmission
Postsynaptic Potential Summation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptic Transmission" by people in this website by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.

Bar chart showing 87 publications over 24 distinct years, with a maximum of 10 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	0	1
1993	1	0	1
1996	0	1	1
1998	1	0	1
2001	1	0	1
2002	3	0	3
2003	1	2	3
2004	1	3	4
2005	3	2	5
2006	2	3	5
2007	3	6	9
2008	5	5	10
2009	0	4	4
2010	0	5	5
2011	0	1	1
2012	5	2	7
2013	2	3	5
2014	3	3	6
2015	2	0	2
2016	1	1	2
2017	3	0	3
2018	3	1	4
2019	1	1	2
2021	0	2	2

Below are the most recent publications written about "Synaptic Transmission" by people in Profiles.

Cleary CM, Milla BM, Kuo FS, James S, Flynn WF, Robson P, Mulkey DK. Somatostatin-expressing parafacial neurons are CO2/H+ sensitive and regulate baseline breathing. Elife. 2021 05 20; 10.

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Ji N, Venkatachalam V, Rodgers HD, Hung W, Kawano T, Clark CM, Lim M, Alkema MJ, Zhen M, Samuel AD. Corollary discharge promotes a sustained motor state in a neural circuit for navigation. Elife. 2021 04 21; 10.

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Huang YC, Pirri JK, Rayes D, Gao S, Mulcahy B, Grant J, Saheki Y, Francis MM, Zhen M, Alkema MJ. Gain-of-function mutations in the UNC-2/CaV2? channel lead to excitation-dominant synaptic transmission in Caenorhabditis elegans. Elife. 2019 08 05; 8.

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Ghasemi M. Nitric oxide: Antidepressant mechanisms and inflammation. Adv Pharmacol. 2019; 86:121-152.

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Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):9002-9007.

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Philbrook A, Ramachandran S, Lambert CM, Oliver D, Florman J, Alkema MJ, Lemons M, Francis MM. Neurexin directs partner-specific synaptic connectivity in C. elegans. Elife. 2018 07 24; 7.

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Mao W, Salzberg AC, Uchigashima M, Hasegawa Y, Hock H, Watanabe M, Akbarian S, Kawasawa YI, Futai K. Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1. Cell Rep. 2018 06 12; 23(11):3209-3222.

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Ghasemi M, Claunch J, Niu K. Pathologic role of nitrergic neurotransmission in mood disorders. Prog Neurobiol. 2019 02; 173:54-87.

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Werneburg S, Feinberg PA, Johnson KM, Schafer DP. A microglia-cytokine axis to modulate synaptic connectivity and function. Curr Opin Neurobiol. 2017 12; 47:138-145.

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Ji X, Saha S, Kolpakova J, Guildford M, Tapper AR, Martin GE. Dopamine Receptors Differentially Control Binge Alcohol Drinking-Mediated Synaptic Plasticity of the Core Nucleus Accumbens Direct and Indirect Pathways. J Neurosci. 2017 05 31; 37(22):5463-5474.

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