CHO Cells

"CHO Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.

Descriptor ID	D016466
MeSH Number(s)	A11.251.210.200 A11.436.155
Concept/Terms	CHO Cells CHO Cells CHO Cell Cell, CHO Cells, CHO

Below are MeSH descriptors whose meaning is more general than "CHO Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
CHO Cells [A11.251.210.200]
Epithelial Cells [A11.436]
CHO Cells [A11.436.155]

Below are MeSH descriptors whose meaning is related to "CHO Cells".

Below are MeSH descriptors whose meaning is more specific than "CHO Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CHO Cells" by people in this website by year, and whether "CHO Cells" was a major or minor topic of these publications.

Bar chart showing 154 publications over 29 distinct years, with a maximum of 16 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	3	3
1996	0	2	2
1997	0	5	5
1998	0	5	5
1999	1	8	9
2000	0	7	7
2001	1	11	12
2002	0	16	16
2003	0	5	5
2004	0	7	7
2005	0	8	8
2006	0	10	10
2007	0	6	6
2008	0	2	2
2009	0	3	3
2010	0	3	3
2011	0	6	6
2013	0	6	6
2014	0	4	4
2015	0	5	5
2016	0	2	2
2017	0	7	7
2018	0	3	3
2019	0	5	5
2020	0	3	3
2021	0	5	5
2022	0	2	2
2023	0	1	1
2024	0	2	2

Below are the most recent publications written about "CHO Cells" by people in Profiles.

Mpakali A, Barla I, Lu L, Ramesh KM, Thomaidis N, Stern LJ, Giastas P, Stratikos E. Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. J Mol Biol. 2024 03 15; 436(6):168449.

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Guay KP, Ke H, Gierasch LM, Gershenson A, Hebert DN. Monitoring the Secretion and Activity of Alpha-1 Antitrypsin in Various Mammalian Cell Types. Methods Mol Biol. 2024; 2750:143-163.

View in: PubMed
Polanco A, Liang G, Park S, Wang Y, Graham RJ, Yoon S. Trace metal optimization in CHO cell culture through statistical design of experiments. Biotechnol Prog. 2023 Nov-Dec; 39(6):e3368.

View in: PubMed
Hoang D, Kuang B, Liang G, Wang Z, Yoon S. Modulation of nutrient precursors for controlling metabolic inhibitors by genome-scale flux balance analysis. Biotechnol Prog. 2023 03; 39(2):e3313.

View in: PubMed
Ke H, Guay KP, Flotte TR, Gierasch LM, Gershenson A, Hebert DN. Secretion of functional a1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2206103119.

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Morris C, Madhavarao CN, Yoon S, Ashraf M. Single in-line biomass probe detects CHO cell growth by capacitance and bacterial contamination by conductivity in bioreactor. Biotechnol J. 2021 Dec; 16(12):e2100126.

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Bharadwaj R, Bhattacharya A. Coordinated activity of amoebic formin and profilin are essential for phagocytosis. Mol Microbiol. 2021 09; 116(3):974-995.

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Hoang D, Galbraith S, Kuang B, Johnson A, Yoon S. Characterization of Chinese hamster ovary cell culture feed media precipitate. Biotechnol Prog. 2021 09; 37(5):e3188.

View in: PubMed
Graham RJ, Mohammad A, Liang G, Fu Q, Kuang B, Polanco A, Lee YS, Marcus RK, Yoon S. Effect of iron addition on mAb productivity and oxidative stress in Chinese hamster ovary culture. Biotechnol Prog. 2021 09; 37(5):e3181.

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McMahon O, Hallam TM, Patel S, Harris CL, Menny A, Zelek WM, Widjajahakim R, Java A, Cox TE, Tzoumas N, Steel DHW, Shuttleworth VG, Smith-Jackson K, Brocklebank V, Griffiths H, Cree AJ, Atkinson JP, Lotery AJ, Bubeck D, Morgan BP, Marchbank KJ, Seddon JM, Kavanagh D. The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. Hum Mol Genet. 2021 06 17; 30(13):1188-1199.

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