Bradykinin

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"Bradykinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.

Descriptor ID	D001920
MeSH Number(s)	D12.644.276.812.169 D12.644.400.090 D12.644.456.193 D12.776.467.812.169 D12.776.631.650.090 D23.469.050.375.110 D23.529.812.169
Concept/Terms	Bradykinin Bradykinin Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg Arg Pro Pro Gly Phe Ser Pro Phe Arg Bradykinin Diacetate Bradykinin Diacetate Bradykinin Hydrochloride Bradykinin Hydrochloride Bradykinin Triacetate Bradykinin Triacetate Bradykinin, (1-D-Arg)-Isomer Bradykinin, (1-D-Arg)-Isomer Bradykinin, (2-D-Pro)-Isomer Bradykinin, (2-D-Pro)-Isomer Bradykinin, (2-D-Pro-3-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-3-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-7-D-Pro)-Isomer Bradykinin, (2-D-Pro-7-D-Pro)-Isomer Bradykinin, (3-D-Pro)-Isomer Bradykinin, (3-D-Pro)-Isomer Bradykinin, (3-D-Pro-7-D-Pro)-Isomer Bradykinin, (3-D-Pro-7-D-Pro)-Isomer Bradykinin, (5-D-Phe)-Isomer Bradykinin, (5-D-Phe)-Isomer Bradykinin, (5-D-Phe-8-D-Phe)-Isomer Bradykinin, (5-D-Phe-8-D-Phe)-Isomer Bradykinin, (6-D-Ser)-Isomer Bradykinin, (6-D-Ser)-Isomer Bradykinin, (7-D-Pro)-Isomer Bradykinin, (7-D-Pro)-Isomer Bradykinin, (8-D-Phe)-Isomer Bradykinin, (8-D-Phe)-Isomer Bradykinin, (9-D-Arg)-Isomer Bradykinin, (9-D-Arg)-Isomer Bradykinin Acetate, (9-D-Arg)-Isomer Bradykinin Acetate, (9-D-Arg)-Isomer

Below are MeSH descriptors whose meaning is more general than "Bradykinin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Kinins [D12.644.276.812]
Bradykinin [D12.644.276.812.169]
Neuropeptides [D12.644.400]
Bradykinin [D12.644.400.090]
Oligopeptides [D12.644.456]
Bradykinin [D12.644.456.193]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Kinins [D12.776.467.812]
Bradykinin [D12.776.467.812.169]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Bradykinin [D12.776.631.650.090]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Kinins [D23.469.050.375]
Bradykinin [D23.469.050.375.110]
Intercellular Signaling Peptides and Proteins [D23.529]
Kinins [D23.529.812]
Bradykinin [D23.529.812.169]

Below are MeSH descriptors whose meaning is related to "Bradykinin".

Below are MeSH descriptors whose meaning is more specific than "Bradykinin".

Bradykinin
Kallidin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bradykinin" by people in this website by year, and whether "Bradykinin" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
2000	0	1	1
2015	1	0	1
2018	1	0	1
2023	1	0	1

Below are the most recent publications written about "Bradykinin" by people in Profiles.

Alves SAS, Teixeira DE, Peruchetti DB, Silva LS, Brand?o LFP, Caruso-Neves C, Pinheiro AAS. Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells. Brain Res. 2024 01 01; 1822:148669.

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Seliga A, Lee MH, Fernandes NC, Zuluaga-Ramirez V, Didukh M, Persidsky Y, Potula R, Gallucci S, Sriram U. Kallikrein-Kinin System Suppresses Type I Interferon Responses: A Novel Pathway of Interferon Regulation. Front Immunol. 2018; 9:156.

View in: PubMed
Silva AF, Alves FL, Pedron CN, Torres MD, Silva LS, Pinheiro AA, Miranda A, Oliveira VX. Anti-plasmodial activity of bradykinin and analogs. Bioorg Med Chem Lett. 2015 Aug 15; 25(16):3311-3.

View in: PubMed
ZhuGe R, Fogarty KE, Tuft RA, Lifshitz LM, Sayar K, Walsh JV. Dynamics of signaling between Ca(2+) sparks and Ca(2+)- activated K(+) channels studied with a novel image-based method for direct intracellular measurement of ryanodine receptor Ca(2+) current. J Gen Physiol. 2000 Dec; 116(6):845-64.

View in: PubMed
ZhuGe R, Sims SM, Tuft RA, Fogarty KE, Walsh JV. Ca2+ sparks activate K+ and Cl- channels, resulting in spontaneous transient currents in guinea-pig tracheal myocytes. J Physiol. 1998 Dec 15; 513 ( Pt 3):711-8.

View in: PubMed
Keeting PE, Li CH, Murty M, Xu J, Cissel DS, Whipkey DL, Graeber GM, Blaha JD. Arachidonic acid metabolism by adult human osteoblast-like cells exhibits sexually dimorphic characteristics. J Cell Biochem. 1998 Oct 01; 71(1):74-81.

View in: PubMed
Donahue JK, Kikkawa K, Thomas AD, Marban E, Lawrence JH. Acceleration of widespread adenoviral gene transfer to intact rabbit hearts by coronary perfusion with low calcium and serotonin. Gene Ther. 1998 May; 5(5):630-4.

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Cissel DS, Murty M, Whipkey DL, Blaha JD, Graeber GM, Keeting PE. Estrogen pretreatment increases arachidonic acid release by bradykinin stimulated normal human osteoblast-like cells. J Cell Biochem. 1996 Feb; 60(2):260-70.

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Miller LA, Cochrane DE, Carraway RE, Feldberg RS. Blockade of mast cell histamine secretion in response to neurotensin by SR 48692, a nonpeptide antagonist of the neurotensin brain receptor. Br J Pharmacol. 1995 Apr; 114(7):1466-70.

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Miller LA, Cochrane DE, Carraway RE, Feldberg RS. Inhibitory effects of the neurotensin8-13 analogs Asp13-NT8-13 and Asp12-NT8-13 on mast cell secretion. Agents Actions. 1993 Jan; 38(1-2):1-7.

View in: PubMed

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