Protein Synthesis Inhibitors

"Protein Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.

Descriptor ID	D011500
MeSH Number(s)	D27.505.519.389.760
Concept/Terms	Protein Synthesis Inhibitors Protein Synthesis Inhibitors Inhibitors, Protein Synthesis Protein Synthesis Antagonists Antagonists, Protein Synthesis

Below are MeSH descriptors whose meaning is more general than "Protein Synthesis Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Protein Synthesis Inhibitors [D27.505.519.389.760]

Below are MeSH descriptors whose meaning is related to "Protein Synthesis Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Protein Synthesis Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Synthesis Inhibitors" by people in this website by year, and whether "Protein Synthesis Inhibitors" was a major or minor topic of these publications.

Bar chart showing 24 publications over 13 distinct years, with a maximum of 4 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	2	2
1998	0	3	3
1999	0	1	1
2000	0	1	1
2001	0	3	3
2002	0	4	4
2004	0	1	1
2005	2	1	3
2007	0	1	1
2012	0	1	1
2013	0	2	2
2017	0	1	1
2022	0	1	1

Below are the most recent publications written about "Protein Synthesis Inhibitors" by people in Profiles.

Mill CP, Fiskus W, DiNardo CD, Birdwell C, Davis JA, Kadia TM, Takahashi K, Short N, Daver N, Ohanian M, Borthakur G, Kornblau SM, Green MR, Qi Y, Su X, Khoury JD, Bhalla KN. Effective therapy for AML with RUNX1 mutation by cotreatment with inhibitors of protein translation and BCL2. Blood. 2022 02 10; 139(6):907-921.

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Peukert K, Steinhagen F, Fox M, Feuerborn C, Schulz S, Seeliger B, Schuss P, Schneider M, Frede S, Sauer A, Putensen C, Latz E, Wilhelm C, Bode C. Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1. Respir Res. 2022 Feb 07; 23(1):21.

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Joshi SS, Tandukar B, Castaneda M, Jiang S, Diwakar G, Hertzano RP, Hornyak TJ. Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors. Gene Expr Patterns. 2018 01; 27:76-84.

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Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PEA, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, Wolozin B. Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Cell Rep. 2016 05 17; 15(7):1455-1466.

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Swanger SA, He YA, Richter JD, Bassell GJ. Dendritic GluN2A synthesis mediates activity-induced NMDA receptor insertion. J Neurosci. 2013 May 15; 33(20):8898-908.

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Ma H, Pederson T. The nucleolus stress response is coupled to an ATR-Chk1-mediated G2 arrest. Mol Biol Cell. 2013 May; 24(9):1334-42.

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Keeling KM, Wang D, Conard SE, Bedwell DM. Suppression of premature termination codons as a therapeutic approach. Crit Rev Biochem Mol Biol. 2012 Sep; 47(5):444-63.

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Suckow AT, Craige B, Faundez V, Cain WJ, Chessler SD. An AP-3-dependent mechanism drives synaptic-like microvesicle biogenesis in pancreatic islet beta-cells. Am J Physiol Endocrinol Metab. 2010 Jul; 299(1):E23-32.

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Colombrita C, Zennaro E, Fallini C, Weber M, Sommacal A, Buratti E, Silani V, Ratti A. TDP-43 is recruited to stress granules in conditions of oxidative insult. J Neurochem. 2009 Nov; 111(4):1051-61.

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Krashes MJ, Waddell S. Rapid consolidation to a radish and protein synthesis-dependent long-term memory after single-session appetitive olfactory conditioning in Drosophila. J Neurosci. 2008 Mar 19; 28(12):3103-13.

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