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Mice, Inbred CFTR

"Mice, Inbred CFTR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.


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This graph shows the total number of publications written about "Mice, Inbred CFTR" by people in this website by year, and whether "Mice, Inbred CFTR" was a major or minor topic of these publications.
Bar chart showing 3 publications over 2 distinct years, with a maximum of 2 publications in 2008
To see the data from this visualization as text, click here.
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