Vitreoretinopathy, Proliferative
"Vitreoretinopathy, Proliferative" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
Descriptor ID |
D018630
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MeSH Number(s) |
C11.768.890
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Concept/Terms |
Vitreoretinopathy, Proliferative- Vitreoretinopathy, Proliferative
- Proliferative Vitreoretinopathies
- Vitreoretinopathies, Proliferative
- Vitreoretinopathy Neovascular Inflammatory
- Inflammatories, Vitreoretinopathy Neovascular
- Inflammatory, Vitreoretinopathy Neovascular
- Neovascular Inflammatories, Vitreoretinopathy
- Neovascular Inflammatory, Vitreoretinopathy
- Vitreoretinopathy Neovascular Inflammatories
- Proliferative Vitreoretinopathy
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Below are MeSH descriptors whose meaning is more general than "Vitreoretinopathy, Proliferative".
Below are MeSH descriptors whose meaning is more specific than "Vitreoretinopathy, Proliferative".
This graph shows the total number of publications written about "Vitreoretinopathy, Proliferative" by people in this website by year, and whether "Vitreoretinopathy, Proliferative" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Vitreoretinopathy, Proliferative" by people in Profiles.
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Jusufbegovic D, Gambrell JD, Barak Y, Schaal S. Twenty-five-gauge vitrectomy for the removal of 5000 centistokes silicone oil. Retina. 2013 Oct; 33(9):1938-42.
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Velez G, Weingarden AR, Lei H, Kazlauskas A, Gao G. SU9518 inhibits proliferative vitreoretinopathy in fibroblast and genetically modified M?ller cell-induced rabbit models. Invest Ophthalmol Vis Sci. 2013 Feb 19; 54(2):1392-7.
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Lei H, Rh?aume MA, Velez G, Mukai S, Kazlauskas A. Expression of PDGFRa is a determinant of the PVR potential of ARPE19 cells. Invest Ophthalmol Vis Sci. 2011 Aug 24; 52(9):5016-21.
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Lei H, Velez G, Kazlauskas A. Pathological signaling via platelet-derived growth factor receptor {alpha} involves chronic activation of Akt and suppression of p53. Mol Cell Biol. 2011 May; 31(9):1788-99.
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Lei H, Velez G, Cui J, Samad A, Maberley D, Matsubara J, Kazlauskas A. N-acetylcysteine suppresses retinal detachment in an experimental model of proliferative vitreoretinopathy. Am J Pathol. 2010 Jul; 177(1):132-40.
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Zahn G, Volk K, Lewis GP, Vossmeyer D, Stragies R, Heier JS, Daniel PE, Adamis AP, Chapin EA, Fisher SK, Holz FG, L?ffler KU, Knolle J. Assessment of the integrin alpha5beta1 antagonist JSM6427 in proliferative vitreoretinopathy using in vitro assays and a rabbit model of retinal detachment. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):1028-35.
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Lei H, Velez G, Hovland P, Hirose T, Gilbertson D, Kazlauskas A. Growth factors outside the PDGF family drive experimental PVR. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3394-403.
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Lei H, Velez G, Hovland P, Hirose T, Kazlauskas A. Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):42-8.
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Lei H, Hovland P, Velez G, Haran A, Gilbertson D, Hirose T, Kazlauskas A. A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2007 May; 48(5):2335-42.