Tryptophan

"Tryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Descriptor ID	D014364
MeSH Number(s)	D12.125.072.050.850 D12.125.142.875
Concept/Terms	Tryptophan Tryptophan L-Tryptophan L Tryptophan Levotryptophan Ardeydorm Ardeydorm Ardeytropin L-Tryptophan-ratiopharm L-Tryptophan-ratiopharm L Tryptophan ratiopharm ratio-Tryptophan ratio Tryptophan Tryptophan Metabolism Alterations Tryptophan Metabolism Alterations PMS-Tryptophan PMS-Tryptophan PMS Tryptophan Trofan Trofan Tryptacin Tryptacin Tryptan Tryptan Optimax Optimax Lyphan Lyphan Naturruhe

Below are MeSH descriptors whose meaning is more general than "Tryptophan".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Cyclic [D12.125.072]
Amino Acids, Aromatic [D12.125.072.050]
Tryptophan [D12.125.072.050.850]
Amino Acids, Essential [D12.125.142]
Tryptophan [D12.125.142.875]

Below are MeSH descriptors whose meaning is related to "Tryptophan".

Below are MeSH descriptors whose meaning is more specific than "Tryptophan".

Tryptophan
5-Hydroxytryptophan

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tryptophan" by people in this website by year, and whether "Tryptophan" was a major or minor topic of these publications.

Bar chart showing 46 publications over 23 distinct years, with a maximum of 5 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	2	0	2
1999	0	1	1
2001	0	2	2
2002	1	1	2
2003	0	1	1
2004	2	1	3
2005	1	0	1
2006	1	0	1
2008	1	1	2
2010	1	2	3
2011	0	2	2
2012	1	1	2
2013	1	0	1
2014	0	1	1
2015	1	0	1
2016	0	2	2
2017	2	0	2
2018	1	2	3
2019	1	2	3
2020	3	2	5
2023	0	4	4
2024	1	0	1

Below are the most recent publications written about "Tryptophan" by people in Profiles.

Duran-Padilla M, Serrano-Loyola R, Perez-Garcia A, Carrillo-Betancourt R, Campos-Garc?a Rojas C, Reyes-Alberto M, Franco W, Hernandez-Ruiz J, Gutierrez-Herrera E. Tryptophan intrinsic fluorescence from wound healing correlates with re-epithelialization in a rabbit model. Skin Res Technol. 2024 Jul; 30(7):e13834.

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Hu Y, Li J, Wang B, Zhu L, Li Y, Ivey KL, Lee KH, Eliassen AH, Chan A, Huttenhower C, Hu FB, Qi Q, Rimm EB, Sun Q. Interplay between diet, circulating indolepropionate concentrations and cardiometabolic health in US populations. Gut. 2023 11 24; 72(12):2260-2271.

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Liu Y, Xiao H, Wang Z, Pan Q, Zhao X, Lu B. Interactions between dietary cholesterol and intestinal flora and their effects on host health. Crit Rev Food Sci Nutr. 2025; 65(3):494-506.

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Mrdjen M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell M, Radaeva S, Barton B, Szabo G, Dasarathy S, Wang Z, Hazen SL, Brown JM, Nagy LE. Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease. Hepatol Commun. 2023 11 01; 7(11).

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Wu Y, Cao X, Du H, Guo X, Han Y, McClements DJ, Decker E, Xing B, Xiao H. Adverse effects of titanium dioxide nanoparticles on beneficial gut bacteria and host health based on untargeted metabolomics analysis. Environ Res. 2023 07 01; 228:115921.

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Souza AG, Bastos VAF, Fujimura PT, Ferreira ICC, Leal LF, da Silva LS, Laus AC, Reis RM, Martins MM, Santos PS, Corr?a NCR, Marangoni K, Thom? CH, Colli LM, Goulart LR, Goulart VA. Cell-free DNA promotes malignant transformation in non-tumor cells. Sci Rep. 2020 12 10; 10(1):21674.

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Voils SA, Shoulders BR, Singh S, Solberg LM, Garrett TJ, Frye RF. Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism. Pharmacotherapy. 2020 06; 40(6):500-506.

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Yao J, Wang J, Wu L, Lu H, Wang Z, Yu P, Xiao H, Gao R, Yu J. Perinatal exposure to bisphenol A causes a disturbance of neurotransmitter metabolic pathways in female mouse offspring: A focus on the tryptophan and dopamine pathways. Chemosphere. 2020 Sep; 254:126715.

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Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M. Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. PLoS Biol. 2020 03; 18(3):e3000618.

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Gutierrez-Herrera E, S?nchez-P?rez C, Perez-Garcia A, Padilla-Castaneda MA, Franco W, Hern?ndez-Ruiz J. Endogenous Fluorescence Dissimilarity Assessment of Four Potential Biomarkers of Early Liver Fibrosis by Preservation Media Effect. J Fluoresc. 2020 Mar; 30(2):249-257.

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