Capsid

"Capsid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The outer protein protective shell of a virus, which protects the viral nucleic acid.

Descriptor ID	D002213
MeSH Number(s)	A21.249.500.250 B04.950.500.250
Concept/Terms	Capsid Capsid Capsids

Below are MeSH descriptors whose meaning is more general than "Capsid".

Anatomy [A]
Viral Structures [A21]
Virion [A21.249]
Nucleocapsid [A21.249.500]
Capsid [A21.249.500.250]
Organisms [B]
Viruses [B04]
Virion [B04.950]
Nucleocapsid [B04.950.500]
Capsid [B04.950.500.250]

Below are MeSH descriptors whose meaning is related to "Capsid".

Below are MeSH descriptors whose meaning is more specific than "Capsid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Capsid" by people in this website by year, and whether "Capsid" was a major or minor topic of these publications.

Bar chart showing 60 publications over 27 distinct years, with a maximum of 5 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	2	0	2
1997	0	1	1
1998	1	0	1
1999	1	0	1
2000	2	1	3
2001	1	0	1
2002	2	1	3
2003	0	1	1
2004	0	2	2
2005	0	3	3
2006	1	1	2
2007	1	0	1
2008	0	2	2
2009	1	1	2
2011	1	1	2
2012	3	2	5
2013	2	1	3
2014	1	0	1
2015	2	0	2
2016	1	0	1
2017	2	1	3
2019	3	1	4
2020	3	1	4
2022	0	1	1
2023	0	3	3
2024	2	2	4

Below are the most recent publications written about "Capsid" by people in Profiles.

Padron A, Dwivedi R, Chakraborty R, Prakash P, Kim K, Shi J, Ahn J, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Cyclophilin A facilitates HIV-1 integration. J Virol. 2024 Nov 19; 98(11):e0094724.

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Fu Q, Wang Y, Qin J, Xie D, McNally D, Yoon S. Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells. Appl Microbiol Biotechnol. 2024 Sep 04; 108(1):459.

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Cui M, Su Q, Yip M, McGowan J, Punzo C, Gao G, Tai PWL. The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2. Gene Ther. 2024 Sep; 31(9-10):489-498.

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Suk Lee Y, Lee J, Fang K, Gee GV, Rogers B, McNally D, Yoon S. Separation of full, empty, and partial adeno-associated virus capsids via anion-exchange chromatography with continuous recycling and accumulation. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Jul 15; 1242:124206.

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Fu Q, Lee YS, Green EA, Wang Y, Park SY, Polanco A, Lee KH, Betenbaugh M, McNally D, Yoon S. Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing. Biotechnol Bioeng. 2023 Nov; 120(11):3148-3162.

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Xue G, Yu HJ, Buffone C, Huang SW, Lee K, Goh SL, Gres AT, Guney MH, Sarafianos SG, Luban J, Diaz-Griffero F, KewalRamani VN. The HIV-1 capsid core is an opportunistic nuclear import receptor. Nat Commun. 2023 06 24; 14(1):3782.

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Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors. Front Immunol. 2023; 14:1105617.

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Hufziger KA, Farquharson EL, Werner BG, Chen Q, Goddard JM, Nugen SR. In Vivo Capsid Engineering of Bacteriophages for Oriented Surface Conjugation. ACS Appl Bio Mater. 2022 11 21; 5(11):5104-5112.

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Hsu HL, Brown A, Loveland AB, Lotun A, Xu M, Luo L, Xu G, Li J, Ren L, Su Q, Gessler DJ, Wei Y, Tai PWL, Korostelev AA, Gao G. Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties. Nat Commun. 2020 06 30; 11(1):3279.

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Ohainle M, Kim K, Komurlu Keceli S, Felton A, Campbell E, Luban J, Emerman M. TRIM34 restricts HIV-1 and SIV capsids in a TRIM5a-dependent manner. PLoS Pathog. 2020 04; 16(4):e1008507.

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