Lymphocyte Depletion

"Lymphocyte Depletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Immunosuppression by reduction of circulating lymphocytes or by T-cell depletion of bone marrow. The former may be accomplished in vivo by thoracic duct drainage or administration of antilymphocyte serum. The latter is performed ex vivo on bone marrow before its transplantation.

Descriptor ID	D008212
MeSH Number(s)	E02.095.465.425.450.521 E05.478.610.570
Concept/Terms	Lymphocyte Depletion Lymphocyte Depletion Depletion, Lymphocyte

Below are MeSH descriptors whose meaning is more general than "Lymphocyte Depletion".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Biological Therapy [E02.095]
Immunomodulation [E02.095.465]
Immunotherapy [E02.095.465.425]
Immunosuppression [E02.095.465.425.450]
Lymphocyte Depletion [E02.095.465.425.450.521]
Investigative Techniques [E05]
Immunologic Techniques [E05.478]
Immunosuppression [E05.478.610]
Lymphocyte Depletion [E05.478.610.570]

Below are MeSH descriptors whose meaning is related to "Lymphocyte Depletion".

Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Depletion".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lymphocyte Depletion" by people in this website by year, and whether "Lymphocyte Depletion" was a major or minor topic of these publications.

Bar chart showing 50 publications over 24 distinct years, with a maximum of 7 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	4	5
1995	0	3	3
1996	0	4	4
1998	0	1	1
1999	1	0	1
2000	2	2	4
2001	0	7	7
2002	0	1	1
2003	0	3	3
2004	0	2	2
2006	0	1	1
2007	0	1	1
2008	1	0	1
2009	0	1	1
2010	2	1	3
2011	0	2	2
2012	0	1	1
2013	0	1	1
2014	0	1	1
2015	0	3	3
2017	0	1	1
2020	0	1	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Lymphocyte Depletion" by people in Profiles.

Gao KM, Motwani M, Tedder T, Marshak-Rothstein A, Fitzgerald KA. Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFN?-dependent mortality in STING gain-of-function mice. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2202327119.

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Kim K, Wang X, Ragonnaud E, Bodogai M, Illouz T, DeLuca M, McDevitt RA, Gusev F, Okun E, Rogaev E, Biragyn A. Therapeutic B-cell depletion reverses progression of Alzheimer's disease. Nat Commun. 2021 04 12; 12(1):2185.

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Lovewell RR, Baer CE, Mishra BB, Smith CM, Sassetti CM. Granulocytes act as a niche for Mycobacterium tuberculosis growth. Mucosal Immunol. 2021 01; 14(1):229-241.

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Merriam D, Chen C, M?ndez-Lagares G, Rogers KA, Michaels AJ, Yan J, Casaz P, Reimann KA, Villinger F, Hartigan-O'Connor DJ. Depletion of Gut-Resident CCR5+ Cells for HIV Cure Strategies. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S70-S80.

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Wang Q, Racine JJ, Ratiu JJ, Wang S, Ettinger R, Wasserfall C, Atkinson MA, Serreze DV. Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy. J Immunol. 2017 12 01; 199(11):3757-3770.

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Scheuplein F, Lamont DJ, Poynter ME, Boyson JE, Serreze D, Lundblad LK, Mashal R, Schaub R. Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo. PLoS One. 2015; 10(10):e0140729.

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Fiume G, Scialdone A, Albano F, Rossi A, Tuccillo FM, Rea D, Palmieri C, Caiazzo E, Cicala C, Bellevicine C, Falcone C, Vecchio E, Pisano A, Ceglia S, Mimmi S, Iaccino E, de Laurentiis A, Pontoriero M, Agosti V, Troncone G, Mignogna C, Palma G, Arra C, Mallardo M, Buonaguro FM, Scala G, Quinto I. Impairment of T cell development and acute inflammatory response in HIV-1 Tat transgenic mice. Sci Rep. 2015 Sep 07; 5:13864.

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Khera AK, Afkhami S, Lai R, Jeyanathan M, Zganiacz A, Mandur T, Hammill J, Damjanovic D, Xing Z. Role of B Cells in Mucosal Vaccine-Induced Protective CD8+ T Cell Immunity against Pulmonary Tuberculosis. J Immunol. 2015 Sep 15; 195(6):2900-7.

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Potter CS, Wang Z, Silva KA, Kennedy VE, Stearns TM, Burzenski L, Shultz LD, Hogenesch H, Sundberg JP. Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling. PLoS One. 2014; 9(1):e85666.

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Waggoner SN, Daniels KA, Welsh RM. Therapeutic depletion of natural killer cells controls persistent infection. J Virol. 2014 Feb; 88(4):1953-60.

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