"GAP-43 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Descriptor ID |
D019922
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MeSH Number(s) |
D12.776.395.550.400 D12.776.543.550.400 D12.776.631.400
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Concept/Terms |
GAP-43 Protein- GAP-43 Protein
- GAP 43 Protein
- Phosphoprotein B-50
- Phosphoprotein B 50
- GAP-43
- Neuromodulin
- Growth-Associated Protein 43
- Growth Associated Protein 43
- Phosphoprotein pp46
- B-50 Protein
- B 50 Protein
- GAP43 Protein
- Nerve Growth Cone Membrane Protein GAP-43
- Nerve Growth Cone Membrane Protein GAP 43
- Phosphoprotein F1
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Below are MeSH descriptors whose meaning is more general than "GAP-43 Protein".
Below are MeSH descriptors whose meaning is more specific than "GAP-43 Protein".
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Below are the most recent publications written about "GAP-43 Protein" by people in Profiles.
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Fallini C, Donlin-Asp PG, Rouanet JP, Bassell GJ, Rossoll W. Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons. J Neurosci. 2016 Mar 30; 36(13):3811-20.
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Henion TR, Faden AA, Knott TK, Schwarting GA. ?3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium. J Neurosci. 2011 Apr 27; 31(17):6576-86.