"GAP-43 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
| Descriptor ID |
D019922
|
| MeSH Number(s) |
D12.776.395.550.400 D12.776.543.550.400 D12.776.631.400
|
| Concept/Terms |
GAP-43 Protein- GAP-43 Protein
- GAP 43 Protein
- Phosphoprotein B-50
- Phosphoprotein B 50
- GAP-43
- Neuromodulin
- Growth-Associated Protein 43
- Growth Associated Protein 43
- Phosphoprotein pp46
- B-50 Protein
- B 50 Protein
- GAP43 Protein
- Nerve Growth Cone Membrane Protein GAP-43
- Nerve Growth Cone Membrane Protein GAP 43
- Phosphoprotein F1
|
Below are MeSH descriptors whose meaning is more general than "GAP-43 Protein".
Below are MeSH descriptors whose meaning is more specific than "GAP-43 Protein".
This graph shows the total number of publications written about "GAP-43 Protein" by people in this website by year, and whether "GAP-43 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "GAP-43 Protein" by people in Profiles.
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?hrfelt A, Benedet AL, Ashton NJ, Kvartsberg H, Vandijck M, Weiner MW, Trojanowski JQ, Shaw LM, Zetterberg H, Blennow K. Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals. Neurology. 2023 01 17; 100(3):e275-e285.
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Bergstr?m S, Remnest?l J, Yousef J, Olofsson J, Markaki I, Carvalho S, Corvol JC, Kultima K, Kilander L, L?wenmark M, Ingelsson M, Blennow K, Zetterberg H, Nellg?rd B, Brosseron F, Heneka MT, Bosch B, Sanchez-Valle R, M?nberg A, Svenningsson P, Nilsson P. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Ann Clin Transl Neurol. 2021 07; 8(7):1456-1470.
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Fallini C, Donlin-Asp PG, Rouanet JP, Bassell GJ, Rossoll W. Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons. J Neurosci. 2016 Mar 30; 36(13):3811-20.
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Henion TR, Faden AA, Knott TK, Schwarting GA. ?3GnT2 maintains adenylyl cyclase-3 signaling and axon guidance molecule expression in the olfactory epithelium. J Neurosci. 2011 Apr 27; 31(17):6576-86.