Nuclease Protection Assays
"Nuclease Protection Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.
Descriptor ID |
D023282
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MeSH Number(s) |
E05.393.600
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Concept/Terms |
Nuclease Protection Assays- Nuclease Protection Assays
- Assay, Nuclease Protection
- Assays, Nuclease Protection
- Nuclease Protection Assay
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Below are MeSH descriptors whose meaning is more general than "Nuclease Protection Assays".
Below are MeSH descriptors whose meaning is more specific than "Nuclease Protection Assays".
This graph shows the total number of publications written about "Nuclease Protection Assays" by people in this website by year, and whether "Nuclease Protection Assays" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclease Protection Assays" by people in Profiles.
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Pechhold S, Stouffer M, Walker G, Martel R, Seligmann B, Hang Y, Stein R, Harlan DM, Pechhold K. Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection. Nat Biotechnol. 2009 Nov; 27(11):1038-42.
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Banerjee P, Weissleder R, Bogdanov A. Linear polyethyleneimine grafted to a hyperbranched poly(ethylene glycol)-like core: a copolymer for gene delivery. Bioconjug Chem. 2006 Jan-Feb; 17(1):125-31.
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Goldmark JP, Fazzio TG, Estep PW, Church GM, Tsukiyama T. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell. 2000 Oct 27; 103(3):423-33.