Apoptotic Protease-Activating Factor 1
"Apoptotic Protease-Activating Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.
| Descriptor ID |
D053477
|
| MeSH Number(s) |
D12.644.360.024.131.124 D12.644.360.075.358.124 D12.776.157.057.006.124 D12.776.476.024.139.124 D12.776.476.075.358.124
|
| Concept/Terms |
Apoptotic Protease-Activating Factor 1- Apoptotic Protease-Activating Factor 1
- Apoptotic Protease Activating Factor 1
- Apaf-1 Protease-Activating Factor
- Apaf 1 Protease Activating Factor
- Protease-Activating Factor, Apaf-1
- Apoptotic Peptidase Activating Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Apoptotic Protease-Activating Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Apoptotic Protease-Activating Factor 1".
This graph shows the total number of publications written about "Apoptotic Protease-Activating Factor 1" by people in this website by year, and whether "Apoptotic Protease-Activating Factor 1" was a major or minor topic of these publications.
![]()
To see the data from this visualization as text,
click here.
Below are the most recent publications written about "Apoptotic Protease-Activating Factor 1" by people in Profiles.
-
Ioannides AS, Massa V, Ferraro E, Cecconi F, Spitz L, Henderson DJ, Copp AJ. Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death. Dev Biol. 2010 Jan 15; 337(2):351-62.
-
Huh JR, Vernooy SY, Yu H, Yan N, Shi Y, Guo M, Hay BA. Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol. 2004 Jan; 2(1):E15.