 JNK Mitogen-Activated Protein Kinases
"JNK Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.
| Descriptor ID |
D048031
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.513 D08.811.913.696.620.682.700.646.750.374 D12.644.360.450.340 D12.776.476.450.340
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| Concept/Terms |
JNK Mitogen-Activated Protein Kinases- JNK Mitogen-Activated Protein Kinases
- JNK Mitogen Activated Protein Kinases
- jun-NH2-Terminal Kinases
- jun NH2 Terminal Kinases
- jun-NH2-Terminal Kinase
- jun NH2 Terminal Kinase
- c-jun Amino-Terminal Kinase
- Amino-Terminal Kinase, c-jun
- c jun Amino Terminal Kinase
- c-jun N-Terminal Kinase
- N-Terminal Kinase, c-jun
- c jun N Terminal Kinase
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Below are MeSH descriptors whose meaning is more general than "JNK Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "JNK Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "JNK Mitogen-Activated Protein Kinases" by people in this website by year, and whether "JNK Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1998 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 3 | 4 | | 2001 | 1 | 3 | 4 | | 2002 | 0 | 12 | 12 | | 2003 | 2 | 8 | 10 | | 2004 | 4 | 3 | 7 | | 2005 | 2 | 2 | 4 | | 2006 | 6 | 2 | 8 | | 2007 | 2 | 4 | 6 | | 2008 | 4 | 0 | 4 | | 2009 | 1 | 3 | 4 | | 2010 | 3 | 2 | 5 | | 2011 | 3 | 0 | 3 | | 2012 | 2 | 3 | 5 | | 2013 | 2 | 1 | 3 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "JNK Mitogen-Activated Protein Kinases" by people in Profiles.
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Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, Böhm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, Kähne T, Sundaravinayagam D, Wolf MJ, Rehrauer H, Koppe C, Speicher T, Padrissa-Altés S, Maire R, Schattenberg JM, Jeong JS, Liu L, Zwirner S, Boger R, Hüser N, Davis RJ, Müllhaupt B, Moch H, Schulze-Bergkamen H, Clavien PA, Werner S, Borsig L, Luther SA, Jost PJ, Weinlich R, Unger K, Behrens A, Hillert L, Dillon C, Di Virgilio M, Wallach D, Dejardin E, Zender L, Naumann M, Walczak H, Green DR, Lopes M, Lavrik I, Luedde T, Heikenwalder M, Weber A. A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell. 2017 Sep 11; 32(3):342-359.e10.
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Vernia S, Cavanagh-Kyros J, Barrett T, Tournier C, Davis RJ. Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK. Cell Rep. 2016 Mar 15; 14(10):2273-80.
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Fogarty CE, Diwanji N, Lindblad JL, Tare M, Amcheslavsky A, Makhijani K, Brückner K, Fan Y, Bergmann A. Extracellular Reactive Oxygen Species Drive Apoptosis-Induced Proliferation via Drosophila Macrophages. Curr Biol. 2016 Mar 07; 26(5):575-84.
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Liu X, Li H, Rajurkar M, Li Q, Cotton JL, Ou J, Zhu LJ, Goel HL, Mercurio AM, Park JS, Davis RJ, Mao J. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016 Feb 09; 14(5):1169-80.
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Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM, Thorpe CM. Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. Infect Immun. 2015 Oct 19; 84(1):138-48.
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Zhu J, Jiang L, Liu Y, Qian W, Liu J, Zhou J, Gao R, Xiao H, Wang J. MAPK and NF-?B pathways are involved in bisphenol A-induced TNF-a and IL-6 production in BV2 microglial cells. Inflammation. 2015 Apr; 38(2):637-48.
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West RJ, Lu Y, Marie B, Gao FB, Sweeney ST. Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. J Cell Biol. 2015 Mar 30; 208(7):931-47.
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Kim SJ, Chen Z, Chamberlain ND, Essani AB, Volin MV, Amin MA, Volkov S, Gravallese EM, Arami S, Swedler W, Lane NE, Mehta A, Sweiss N, Shahrara S. Ligation of TLR5 promotes myeloid cell infiltration and differentiation into mature osteoclasts in rheumatoid arthritis and experimental arthritis. J Immunol. 2014 Oct 15; 193(8):3902-13.
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Kant S, Barrett T, Vertii A, Noh YH, Jung DY, Kim JK, Davis RJ. Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity. Cell Rep. 2013 Aug 29; 4(4):681-8.
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Sosna J, Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, Herdegen T, Linkermann A, Rittger A, Chan FK, Kabelitz D, Schütze S, Adam D. TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci. 2014 Jan; 71(2):331-48.
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