 Interleukin-6
"Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
| Descriptor ID |
D015850
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| MeSH Number(s) |
D12.644.276.374.465.506 D12.776.467.374.465.506 D23.529.374.465.506
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| Concept/Terms |
Interleukin-6- Interleukin-6
- Interleukin 6
- Plasmacytoma Growth Factor
- Growth Factor, Plasmacytoma
- B-Cell Differentiation Factor-2
- B Cell Differentiation Factor 2
- B-Cell Stimulatory Factor 2
- B-Cell Stimulatory Factor-2
- BSF-2
- Differentiation Factor, B-Cell
- Differentiation Factor, B Cell
- Differentiation Factor-2, B-Cell
- Differentiation Factor 2, B Cell
- Hepatocyte-Stimulating Factor
- Hepatocyte Stimulating Factor
- Hybridoma Growth Factor
- Growth Factor, Hybridoma
- IFN-beta 2
- IL-6
- IL6
- MGI-2
- Myeloid Differentiation-Inducing Protein
- Differentiation-Inducing Protein, Myeloid
- Myeloid Differentiation Inducing Protein
- B Cell Stimulatory Factor-2
- B Cell Stimulatory Factor 2
- B-Cell Differentiation Factor
- B Cell Differentiation Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-6".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-6".
This graph shows the total number of publications written about "Interleukin-6" by people in this website by year, and whether "Interleukin-6" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 2 | 3 | | 1992 | 1 | 1 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 3 | 3 | 6 | | 1997 | 0 | 4 | 4 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 4 | 5 | | 2000 | 1 | 5 | 6 | | 2001 | 1 | 5 | 6 | | 2002 | 2 | 9 | 11 | | 2003 | 1 | 4 | 5 | | 2004 | 1 | 9 | 10 | | 2005 | 3 | 6 | 9 | | 2006 | 2 | 3 | 5 | | 2007 | 4 | 10 | 14 | | 2008 | 2 | 9 | 11 | | 2009 | 0 | 6 | 6 | | 2010 | 3 | 8 | 11 | | 2011 | 2 | 3 | 5 | | 2012 | 2 | 11 | 13 | | 2013 | 5 | 8 | 13 | | 2014 | 3 | 9 | 12 | | 2015 | 2 | 8 | 10 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 2 | 3 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-6" by people in Profiles.
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Zhang X, Yan F, Feng J, Qian H, Cheng Z, Yang Q, Wu Y, Zhao Z, Li A, Xiao H. Dexmedetomidine inhibits inflammatory reaction in the hippocampus of septic rats by suppressing NF-?B pathway. PLoS One. 2018; 13(5):e0196897.
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Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, Larson MG, Levy D. MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage. Circ Cardiovasc Genet. 2017 Oct; 10(5).
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Kim S, Kim H, Yim YS, Ha S, Atarashi K, Tan TG, Longman RS, Honda K, Littman DR, Choi GB, Huh JR. Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature. 2017 09 28; 549(7673):528-532.
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Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial. JAMA. 2017 08 22; 318(8):731-740.
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Li W, Dorans KS, Wilker EH, Rice MB, Ljungman PL, Schwartz JD, Coull BA, Koutrakis P, Gold DR, Keaney JF, Vasan RS, Benjamin EJ, Mittleman MA. Short-Term Exposure to Ambient Air Pollution and Biomarkers of Systemic Inflammation: The Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2017 09; 37(9):1793-1800.
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Sokolova M, Vinge LE, Alfsnes K, Olsen MB, Eide L, Kaasbøll OJ, Attramadal H, Torp MK, Fosshaug LE, Rashidi A, Lien E, Finsen AV, Sandanger Ø, Aukrust P, Ranheim T, Yndestad A. Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. Biochim Biophys Acta. 2017 02; 1862(2):234-245.
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Iani FC, Caldas S, Duarte MM, Cury AL, Cecílio AB, Costa PA, Antonelli LR, Gollob KJ. Dengue Patients with Early Hemorrhagic Manifestations Lose Coordinate Expression of the Anti-Inflammatory Cytokine IL-10 with the Inflammatory Cytokines IL-6 and IL-8. Am J Trop Med Hyg. 2016 07 06; 95(1):193-200.
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Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 Deletion in Macrophages on Proinflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis. J Immunol. 2015 Dec 1; 195(11):5337-46.
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Luo MX, Wong SH, Chan MT, Yu L, Yu SS, Wu F, Xiao Z, Wang X, Zhang L, Cheng AS, Ng SS, Chan FK, Cho CH, Yu J, Sung JJ, Wu WK. Autophagy Mediates HBx-Induced Nuclear Factor-?B Activation and Release of IL-6, IL-8, and CXCL2 in Hepatocytes. J Cell Physiol. 2015 Oct; 230(10):2382-9.
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Singamsetty S, Shah FA, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ. Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice. Appl Physiol Nutr Metab. 2016 Jan; 41(1):12-9.
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