Gene Knockdown Techniques

"Gene Knockdown Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.

Descriptor ID	D055785
MeSH Number(s)	E05.393.335.500
Concept/Terms	Gene Knockdown Techniques Gene Knockdown Techniques Gene Knockdown Technique Knockdown Technique, Gene Knockdown Techniques, Gene Technique, Gene Knockdown Techniques, Gene Knockdown Gene Knockdown Gene Knockdowns Knockdown, Gene Knockdowns, Gene Gene Knock-Down Gene Knock-Downs Knock-Down, Gene Knock-Downs, Gene Gene Knock-Down Techniques Gene Knock-Down Technique Knock-Down Technique, Gene Knock-Down Techniques, Gene Technique, Gene Knock-Down Techniques, Gene Knock-Down Gene Knock Down Gene Knock Downs Knock Down, Gene Knock Downs, Gene Gene Knock Down Techniques

Below are MeSH descriptors whose meaning is more general than "Gene Knockdown Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Gene Targeting [E05.393.335]
Gene Knockdown Techniques [E05.393.335.500]

Below are MeSH descriptors whose meaning is related to "Gene Knockdown Techniques".

Below are MeSH descriptors whose meaning is more specific than "Gene Knockdown Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Knockdown Techniques" by people in this website by year, and whether "Gene Knockdown Techniques" was a major or minor topic of these publications.

Bar chart showing 143 publications over 14 distinct years, with a maximum of 15 publications in 2012 and 2015 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	2	3
2009	1	10	11
2010	0	12	12
2011	0	13	13
2012	1	14	15
2013	0	13	13
2014	1	13	14
2015	1	14	15
2016	1	14	15
2017	2	9	11
2018	0	4	4
2019	0	7	7
2020	0	8	8
2021	0	2	2

Below are the most recent publications written about "Gene Knockdown Techniques" by people in Profiles.

Sonobe Y, Aburas J, Krishnan G, Fleming AC, Ghadge G, Islam P, Warren EC, Gu Y, Kankel MW, Brown AEX, Kiskinis E, Gendron TF, Gao FB, Roos RP, Kratsios P. A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nat Commun. 2021 10 15; 12(1):6025.

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Kour S, Rajan DS, Fortuna TR, Anderson EN, Ward C, Lee Y, Lee S, Shin YB, Chae JH, Choi M, Siquier K, Cantagrel V, Amiel J, Stolerman ES, Barnett SS, Cousin MA, Castro D, McDonald K, Kirmse B, Nemeth AH, Rajasundaram D, Innes AM, Lynch D, Frosk P, Collins A, Gibbons M, Yang M, Desguerre I, Boddaert N, Gitiaux C, Rydning SL, Selmer KK, Urreizti R, Garcia-Oguiza A, Osorio AN, Verdura E, Pujol A, McCurry HR, Landers JE, Agnihotri S, Andriescu EC, Moody SB, Phornphutkul C, Sacoto MJG, Begtrup A, Houlden H, Kirschner J, Schorling D, Rudnik-Sch?neborn S, Strom TM, Leiz S, Juliette K, Richardson R, Yang Y, Zhang Y, Wang M, Wang J, Wang X, Platzer K, Donkervoort S, B?nnemann CG, Wagner M, Issa MY, Elbendary HM, Stanley V, Maroofian R, Gleeson JG, Zaki MS, Senderek J, Pandey UB. Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder. Nat Commun. 2021 05 07; 12(1):2558.

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Uchigashima M, Konno K, Demchak E, Cheung A, Watanabe T, Keener DG, Abe M, Le T, Sakimura K, Sasaoka T, Uemura T, Imamura Kawasawa Y, Watanabe M, Futai K. Specific Neuroligin3-aNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus. Elife. 2020 12 23; 9.

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Agarwal S, Vierbuchen T, Ghosh S, Chan J, Jiang Z, Kandasamy RK, Ricci E, Fitzgerald KA. The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans. Nat Commun. 2020 12 11; 11(1):6348.

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Feng Y, Wang Y, Wang X, He X, Yang C, Naseri A, Pederson T, Zheng J, Zhang S, Xiao X, Xie W, Ma H. Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. Genome Biol. 2020 12 08; 21(1):296.

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Silva-Oliveira G, De Paula IF, Medina JM, Alves-Bezerra M, Gondim KC. Insulin receptor deficiency reduces lipid synthesis and reproductive function in the insect Rhodnius prolixus. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 02; 1866(2):158851.

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Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen Acts Through Estrogen Receptor 2b to Regulate Hepatobiliary Fate During Vertebrate Development. Hepatology. 2020 11; 72(5):1786-1799.

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Sharma RB, Darko C, Alonso LC. Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells. J Biol Chem. 2020 10 09; 295(41):14164-14177.

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Yang T, Zang S, Wang Y, Zhu Y, Jiang L, Chen X, Zhang X, Cheng J, Gao R, Xiao H, Wang J. Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis. Toxicol Lett. 2020 Oct 15; 333:150-158.

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Loring HS, Parelkar SS, Mondal S, Thompson PR. Identification of the first noncompetitive SARM1 inhibitors. Bioorg Med Chem. 2020 09 15; 28(18):115644.

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