A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.

Descriptor ID	D019014
MeSH Number(s)	D12.776.543.750.690.500 D12.776.543.750.705.852.760.195
Concept/Terms	fas Receptor fas Receptor Receptor, fas fas Antigen fas Antigens APO-1 Antigen APO 1 Antigen CD95 Antigen TNFRSF6 Receptor Receptor, TNFRSF6 Antigens, CD95 Receptors, fas fas Receptors Tumor Necrosis Factor Receptor Superfamily, Member 6 Fas Cell Surface Death Receptor CD95 Antigens

Below are MeSH descriptors whose meaning is more general than "fas Receptor".

Below are MeSH descriptors whose meaning is related to "fas Receptor".

Below are MeSH descriptors whose meaning is more specific than "fas Receptor".