Insulator dysfunction and oncogene activation in IDH mutant gliomas.

Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suv? ML, Bernstein BE. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. 2016 Jan 07; 529(7584):110-4.

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subject areas

Base Sequence
Binding Sites
CCCTC-Binding Factor
Cell Cycle Proteins
Cell Proliferation
Cell Transformation, Neoplastic
Cells, Cultured
Chromatin
Chromosomal Proteins, Non-Histone
CpG Islands
CRISPR-Cas Systems
DNA Methylation
Down-Regulation
Enhancer Elements, Genetic
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Glioma
Glutarates
Humans
Insulator Elements
Isocitrate Dehydrogenase
Mutation
Oncogenes
Phenotype
Protein Binding
Receptor, Platelet-Derived Growth Factor alpha
Repressor Proteins
Up-Regulation

authors with profiles

William Alexander Flavahan PhD