Autophagy-Related Protein 5
"Autophagy-Related Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
| Descriptor ID |
D000071187
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| MeSH Number(s) |
D12.776.094.250
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| Concept/Terms |
Autophagy-Related Protein 5- Autophagy-Related Protein 5
- Autophagy Related Protein 5
- Apoptosis-Specific Protein
- Apoptosis Specific Protein
- ATG5 Protein
- ATG-5 Protein
- ATG 5 Protein
- Autophagy Protein-5
- Autophagy Protein 5
- Autophagy-Related 5 Protein
- Autophagy Related 5 Protein
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 5".
This graph shows the total number of publications written about "Autophagy-Related Protein 5" by people in this website by year, and whether "Autophagy-Related Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 5" by people in Profiles.
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Mittal E, Prasad GVRK, Upadhyay S, Sadadiwala J, Olive AJ, Yang G, Sassetti CM, Philips JA. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice. Nat Microbiol. 2024 Nov; 9(11):2970-2984.
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Jin J, Zhu KS, Tang SM, Xiang Y, Mao MY, Hong XD, Chen AF, Zhang XD, Lu H, Chen ZL, Wu JF, Pan SF, Zhu SH. Trehalose promotes functional recovery of keratinocytes under oxidative stress and wound healing via ATG5/ATG7. Burns. 2023 09; 49(6):1382-1391.
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Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, Lacy-Hulbert A. av Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016 Mar 11; 7:10917.
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Behar SM, Baehrecke EH. Tuberculosis: Autophagy is not the answer. Nature. 2015 Dec 24; 528(7583):482-3.
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Rohatgi RA, Janusis J, Leonard D, Bellv? KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015 Oct 16; 34(42):5352-62.
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Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P. Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17071-6.
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Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol. 2011 Oct 16; 13(11):1335-43.