Autophagy-Related Protein 5
"Autophagy-Related Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.
| Descriptor ID |
D000071187
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| MeSH Number(s) |
D12.776.094.250
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| Concept/Terms |
Autophagy-Related Protein 5- Autophagy-Related Protein 5
- Autophagy Related Protein 5
- Apoptosis-Specific Protein
- Apoptosis Specific Protein
- ATG5 Protein
- ATG-5 Protein
- ATG 5 Protein
- Autophagy Protein-5
- Autophagy Protein 5
- Autophagy-Related 5 Protein
- Autophagy Related 5 Protein
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 5".
This graph shows the total number of publications written about "Autophagy-Related Protein 5" by people in this website by year, and whether "Autophagy-Related Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 5" by people in Profiles.
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Mittal E, Prasad GVRK, Upadhyay S, Sadadiwala J, Olive AJ, Yang G, Sassetti CM, Philips JA. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice. Nat Microbiol. 2024 Nov; 9(11):2970-2984.
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Behar SM, Baehrecke EH. Tuberculosis: Autophagy is not the answer. Nature. 2015 Dec 24; 528(7583):482-3.
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Rohatgi RA, Janusis J, Leonard D, Bellv? KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015 Oct 16; 34(42):5352-62.
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Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P. Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17071-6.
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Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes. Nat Cell Biol. 2011 Oct 16; 13(11):1335-43.