"DNA Polymerase gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE.
Descriptor ID |
D000074002
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MeSH Number(s) |
D08.811.913.696.445.308.300.169 D12.776.575.280
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Concept/Terms |
DNA Polymerase gamma- DNA Polymerase gamma
- Polymerase gamma, DNA
- Mitochondrial DNA Polymerase
- DNA Polymerase, Mitochondrial
- Polymerase, Mitochondrial DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Polymerase gamma".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase gamma".
This graph shows the total number of publications written about "DNA Polymerase gamma" by people in this website by year, and whether "DNA Polymerase gamma" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase gamma" by people in Profiles.
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Yang Q, Liu P, Anderson NS, Shpilka T, Du Y, Naresh NU, Li R, Zhu LJ, Luk K, Lavelle J, Zeinert RD, Chien P, Wolfe SA, Haynes CM. LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria. Nat Cell Biol. 2022 02; 24(2):181-193.
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Williams SL, Huang J, Edwards YJ, Ulloa RH, Dillon LM, Prolla TA, Vance JM, Moraes CT, Z?chner S. The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers. Cell Metab. 2010 Dec 01; 12(6):675-82.