Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
Latz E, Franko J, Golenbock DT, Schreiber JR. Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity. J Immunol. 2004 Feb 15; 172(4):2431-8.
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Adaptor Proteins, Signal Transducing
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Animals
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Antibodies, Bacterial
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Antigens, Differentiation
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Bacterial Outer Membrane Proteins
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Bone Marrow Cells
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Carrier Proteins
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Cell Line
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Cells, Cultured
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Cytokines
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Dendritic Cells
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Down-Regulation
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Haemophilus Vaccines
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Humans
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Membrane Glycoproteins
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Mice
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Mice, Inbred C57BL
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Mice, Knockout
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Myeloid Differentiation Factor 88
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Neisseria meningitidis
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Polysaccharides, Bacterial
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Receptors, Cell Surface
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Receptors, Immunologic
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Toll-Like Receptor 2
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Toll-Like Receptors
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Tumor Necrosis Factor-alpha
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Vaccines, Conjugate