"Ursodeoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
Descriptor ID |
D014580
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MeSH Number(s) |
D04.210.500.105.225.272.962 D04.210.500.221.430.342.925
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Concept/Terms |
Ursodeoxycholic Acid- Ursodeoxycholic Acid
- Acid, Ursodeoxycholic
- Ursacholic Acid
- Acid, Ursacholic
- 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid
- 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid
- Ursodiol
- Deoxyursocholic Acid
- Acid, Deoxyursocholic
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Below are MeSH descriptors whose meaning is more general than "Ursodeoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ursodeoxycholic Acid".
This graph shows the total number of publications written about "Ursodeoxycholic Acid" by people in this website by year, and whether "Ursodeoxycholic Acid" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ursodeoxycholic Acid" by people in Profiles.
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Varanasi SK, Chen D, Liu Y, Johnson MA, Miller CM, Ganguly S, Lande K, LaPorta MA, Hoffmann FA, Mann TH, Teneche MG, Casillas E, Mangalhara KC, Mathew V, Sun M, Jensen IJ, Farsakoglu Y, Chen T, Parisi B, Deota S, Havas A, Lee J, Chung HK, Schietinger A, Panda S, Williams AE, Farber DL, Dhar D, Adams PD, Feng GS, Shadel GS, Sundrud MS, Kaech SM. Bile acid synthesis impedes tumor-specific T cell responses during liver cancer. Science. 2025 Jan 10; 387(6730):192-201.
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Pitt HA, Nakeeb A. Prevention of Gallstone Formation After Gastrectomy. JAMA Surg. 2020 08 01; 155(8):712.
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Leyva-Alvizo A, Arredondo-Salda?a G, Leal-Isla-Flores V, Romanelli J, Sudan R, Gibbs KE, Petrick A, Soriano IS. Systematic review of management of gallbladder disease in patients undergoing minimally invasive bariatric surgery. Surg Obes Relat Dis. 2020 Jan; 16(1):158-164.
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Bode N, Grebe A, Kerksiek A, L?tjohann D, Werner N, Nickenig G, Latz E, Zimmer S. Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice. Biochem Biophys Res Commun. 2016 09 09; 478(1):356-362.
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Leftwich H, Fang YM, Borgida A, Crombleholme W. Primary sclerosing cholangitis in pregnancy refractory to ursodeoxycholic acid treatment: a case report. J Reprod Med. 2010 Nov-Dec; 55(11-12):517-9.
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McPartland KJ, Lewis WD, Gordon FD, Pomfret EA, Pomposelli JJ, Jenkins R, Khettry U. Post-liver transplant cholestatic disorder with biliary strictures: de novo versus recurrent primary sclerosing cholangitis. Pathol Int. 2009 May; 59(5):312-6.
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Strauss KA, Robinson DL, Vreman HJ, Puffenberger EG, Hart G, Morton DH. Management of hyperbilirubinemia and prevention of kernicterus in 20 patients with Crigler-Najjar disease. Eur J Pediatr. 2006 May; 165(5):306-19.