Bile Acids and Salts

"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.

Descriptor ID	D001647
MeSH Number(s)	D04.210.500.105
Concept/Terms	Bile Acids and Salts Bile Acids and Salts Bile Acids Bile Acids Acids, Bile Bile Salts Bile Salts Salts, Bile

Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Bile Acids and Salts [D04.210.500.105]

Below are MeSH descriptors whose meaning is related to "Bile Acids and Salts".

Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".

Bile Acids and Salts
Cholic Acids

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.

Bar chart showing 19 publications over 14 distinct years, with a maximum of 4 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2003	1	0	1
2007	1	0	1
2011	0	1	1
2014	2	2	4
2015	1	0	1
2017	0	1	1
2018	2	0	2
2020	1	0	1
2021	0	1	1
2022	0	1	1
2023	0	2	2
2024	1	0	1
2025	1	0	1

Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.

Varanasi SK, Chen D, Liu Y, Johnson MA, Miller CM, Ganguly S, Lande K, LaPorta MA, Hoffmann FA, Mann TH, Teneche MG, Casillas E, Mangalhara KC, Mathew V, Sun M, Jensen IJ, Farsakoglu Y, Chen T, Parisi B, Deota S, Havas A, Lee J, Chung HK, Schietinger A, Panda S, Williams AE, Farber DL, Dhar D, Adams PD, Feng GS, Shadel GS, Sundrud MS, Kaech SM. Bile acid synthesis impedes tumor-specific T cell responses during liver cancer. Science. 2025 01 10; 387(6730):192-201.

View in: PubMed
Zhuang Y, Szabo G. Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known. Hepatology. 2024 07 01; 80(1):E2-E3.

View in: PubMed
Liu Y, Xiao H, Wang Z, Pan Q, Zhao X, Lu B. Interactions between dietary cholesterol and intestinal flora and their effects on host health. Crit Rev Food Sci Nutr. 2025; 65(3):494-506.

View in: PubMed
Zhuang Y, Ortega-Ribera M, Thevkar Nagesh P, Joshi R, Huang H, Wang Y, Zivny A, Mehta J, Parikh SM, Szabo G. Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1. Hepatology. 2024 04 01; 79(4):752-767.

View in: PubMed
Foley SE, Dente MJ, Lei X, Sallis BF, Loew EB, Meza-Segura M, Fitzgerald KA, McCormick BA. Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression. mBio. 2022 08 30; 13(4):e0199322.

View in: PubMed
Henson MA. Computational modeling of the gut microbiota reveals putative metabolic mechanisms of recurrent Clostridioides difficile infection. PLoS Comput Biol. 2021 02; 17(2):e1008782.

View in: PubMed
Dawson HD, Chen C, Li RW, Bell LN, Shea-Donohue T, Kringel H, Beshah E, Hill DE, Urban JF. Molecular and metabolomic changes in the proximal colon of pigs infected with Trichuris suis. Sci Rep. 2020 07 30; 10(1):12853.

View in: PubMed
Manieri E, Folgueira C, Rodr?guez ME, Leiva-Vega L, Esteban-Lafuente L, Chen C, Cubero FJ, Barrett T, Cavanagh-Kyros J, Seruggia D, Rosell A, Sanchez-Cabo F, G?mez MJ, Monte MJ, G Marin JJ, Davis RJ, Mora A, Sabio G. JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16492-16499.

View in: PubMed
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling MA, Motsinger-Reif A, Rotroff DM, Jack J, Hankemeier T, Bennett DA, De Jager PL, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, van Duijn CM, Saykin AJ, Kastenm?ller G, Kaddurah-Daouk R. Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome. Alzheimers Dement. 2019 01; 15(1):76-92.

View in: PubMed
Nho K, Kueider-Paisley A, MahmoudianDehkordi S, Arnold M, Risacher SL, Louie G, Blach C, Baillie R, Han X, Kastenm?ller G, Jia W, Xie G, Ahmad S, Hankemeier T, van Duijn CM, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R. Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers. Alzheimers Dement. 2019 02; 15(2):232-244.

View in: PubMed

People

Explore

Similar Concepts

Top Journals