"Crystallins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. The presence of these proteins accounts for the transparency of the lens. The family is composed of four major groups, alpha, beta, gamma, and delta, and several minor groups, which are classed on the basis of size, charge, immunological properties, and vertebrate source. Alpha, beta, and delta crystallins occur in avian and reptilian lenses, while alpha, beta, and gamma crystallins occur in all other lenses.
Descriptor ID |
D003459
|
MeSH Number(s) |
D12.776.306.366
|
Concept/Terms |
Crystallins- Crystallins
- Lens Proteins
- Proteins, Lens
- Crystallin
|
Below are MeSH descriptors whose meaning is more general than "Crystallins".
Below are MeSH descriptors whose meaning is more specific than "Crystallins".
This graph shows the total number of publications written about "Crystallins" by people in this website by year, and whether "Crystallins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Crystallins" by people in Profiles.
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Duewell P, Latz E. Assessment and quantification of crystal-induced lysosomal damage. Methods Mol Biol. 2013; 1040:19-27.
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Plotnikova OV, Kondrashov FA, Vlasov PK, Grigorenko AP, Ginter EK, Rogaev EI. Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state. Am J Hum Genet. 2007 Jul; 81(1):32-43.
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Anthony SG, Schipper HM, Tavares R, Hovanesian V, Cortez SC, Stopa EG, Johanson CE. Stress protein expression in the Alzheimer-diseased choroid plexus. J Alzheimers Dis. 2003 Jun; 5(3):171-7.
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Kondoh H, Uchikawa M, Yoda H, Takeda H, Furutani-Seiki M, Karlstrom RO. Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage. Mech Dev. 2000 Sep; 96(2):165-74.
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Rogaev EI, Rogaeva EA, Korovaitseva GI, Farrer LA, Petrin AN, Keryanov SA, Turaeva S, Chumakov I, St George-Hyslop P, Ginter EK. Linkage of polymorphic congenital cataract to the gamma-crystallin gene locus on human chromosome 2q33-35. Hum Mol Genet. 1996 May; 5(5):699-703.