High-Throughput Screening Assays

"High-Throughput Screening Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Rapid methods of measuring the effects of an agent in a biological or chemical assay. The assay usually involves some form of automation or a way to conduct multiple assays at the same time using sample arrays.

Descriptor ID	D057166
MeSH Number(s)	E05.916.680
Concept/Terms	High-Throughput Screening Assays High-Throughput Screening Assays Assay, High-Throughput Screening High Throughput Screening Assays High-Throughput Screening Assay Screening Assay, High-Throughput Screening Assays, High-Throughput High-Throughput Screening Methods High-Throughput Screening Methods High Throughput Screening Methods High-Throughput Screening Method Methods, High-Throughput Screening Screening Method, High-Throughput Screening Methods, High-Throughput High-Throughput Biological Assays High-Throughput Biological Assays Assay, High-Throughput Biological Assays, High-Throughput Biological Biological Assay, High-Throughput Biological Assays, High-Throughput High Throughput Biological Assays High-Throughput Biological Assay High-Throughput Chemical Assays High-Throughput Chemical Assays Assay, High-Throughput Chemical Assays, High-Throughput Chemical Chemical Assay, High-Throughput Chemical Assays, High-Throughput High Throughput Chemical Assays High-Throughput Chemical Assay

Below are MeSH descriptors whose meaning is more general than "High-Throughput Screening Assays".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Technology, Pharmaceutical [E05.916]
High-Throughput Screening Assays [E05.916.680]

Below are MeSH descriptors whose meaning is related to "High-Throughput Screening Assays".

Below are MeSH descriptors whose meaning is more specific than "High-Throughput Screening Assays".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "High-Throughput Screening Assays" by people in this website by year, and whether "High-Throughput Screening Assays" was a major or minor topic of these publications.

Bar chart showing 54 publications over 15 distinct years, with a maximum of 7 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	2	0	2
2010	3	0	3
2011	1	1	2
2012	3	1	4
2013	3	4	7
2014	1	2	3
2015	2	4	6
2016	2	2	4
2017	2	2	4
2018	1	0	1
2019	2	1	3
2020	1	2	3
2021	3	3	6
2022	0	1	1
2024	3	2	5

Below are the most recent publications written about "High-Throughput Screening Assays" by people in Profiles.

Elfawal MA, Goetz E, Kim Y, Chen P, Savinov SN, Barasa L, Thompson PR, Aroian RV. High-Throughput Screening of More Than 30,000 Compounds for Anthelmintics against Gastrointestinal Nematode Parasites. ACS Infect Dis. 2025 Jan 10; 11(1):104-120.

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Bozal SB, Sjogren G, Costa AP, Brown JS, Roberts S, Baker D, Gabriel P, Ristau BT, Samuels M, Flynn WF, Robson P, Courtois ET. Development of an automated 3D high content cell screening platform for organoid phenotyping. SLAS Discov. 2024 Oct; 29(7):100182.

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Zhang Y, Li JN, Wang JX, Li YF, Kallenborn R, Xiao H, Cai MG, Tang ZH, Zhang ZF. High-throughput screening of 222 pesticides in road environments in a megacity of northern China: A new approach to urban population exposure. Environ Res. 2024 Sep 15; 257:119379.

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Tang HT, N?rz D, Grunwald M, Giersch K, Pfefferle S, Fischer N, Aepfelbacher M, Rohde H, L?tgehetmann M. Analytical and clinical validation of a novel, laboratory-developed, modular multiplex-PCR panel for fully automated high-throughput detection of 16 respiratory viruses. J Clin Virol. 2024 08; 173:105693.

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Blasco B, Jang S, Terauchi H, Kobayashi N, Suzuki S, Akao Y, Ochida A, Morishita N, Takagi T, Nagamiya H, Suzuki Y, Watanabe T, Lee H, Lee S, Shum D, Cho A, Koh D, Park S, Lee H, Kim K, Ropponen HK, Augusto da Costa RM, Dunn S, Ghosh S, Sj? P, Piddock LJV. High-throughput screening of small-molecules libraries identified antibacterials against clinically relevant multidrug-resistant A.?baumannii and K.?pneumoniae. EBioMedicine. 2024 Apr; 102:105073.

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N?rz D, Grunwald M, Tang HT, Weinschenk C, G?nther T, Robitaille A, Giersch K, Fischer N, Grundhoff A, Aepfelbacher M, Pfefferle S, L?tgehetmann M. Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants. Viruses. 2022 03 15; 14(3).

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Gard AL, Luu RJ, Miller CR, Maloney R, Cain BP, Marr EE, Burns DM, Gaibler R, Mulhern TJ, Wong CA, Alladina J, Coppeta JR, Liu P, Wang JP, Azizgolshani H, Fezzie RF, Balestrini JL, Isenberg BC, Medoff BD, Finberg RW, Borenstein JT. High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro. Sci Rep. 2021 07 22; 11(1):14961.

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Gopal S, Osborne AE, Hock L, Zemianek J, Fang K, Gee G, Ghosh R, McNally D, Cramer SM, Dordick JS. Advancing a rapid, high throughput screening platform for optimization of lentivirus production. Biotechnol J. 2021 Oct; 16(10):e2000621.

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N?rz D, Grunwald M, Olearo F, Fischer N, Aepfelbacher M, Pfefferle S, L?tgehetmann M. Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7. J Clin Virol. 2021 Aug; 141:104894.

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Richards R, Honeywell ME, Lee MJ. FLICK: an optimized plate reader-based assay to infer cell death kinetics. STAR Protoc. 2021 03 19; 2(1):100327.

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