Linoleic Acid

"Linoleic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

Descriptor ID	D019787
MeSH Number(s)	D10.251.355.310.515.500 D10.251.355.343.500.500
Concept/Terms	Linoleic Acid Linoleic Acid 9,12-Octadecadienoic Acid 9,12 Octadecadienoic Acid Acid, 9,12-Octadecadienoic Linoleate Linoleate Linoleic Acid, (Z,E)-Isomer Linoleic Acid, (Z,E)-Isomer Linoleic Acid, (Z,Z)-Isomer Linoleic Acid, (Z,Z)-Isomer cis,cis-9,12-Octadecadienoic Acid Linolelaidic Acid Linolelaidic Acid trans,trans-9,12-Octadecadienoic Acid Linoleic Acid, (E,E)-Isomer 9-trans,12-trans-Octadecadienoic Acid 9 trans,12 trans Octadecadienoic Acid Linoelaidic Acid Linoleic Acid, Ammonium Salt, (Z,Z)-Isomer Linoleic Acid, Ammonium Salt, (Z,Z)-Isomer Linoleic Acid, Calcium Salt, (Z,Z)-Isomer Linoleic Acid, Calcium Salt, (Z,Z)-Isomer Linoleic Acid, Potassium Salt, (Z,Z)-Isomer Linoleic Acid, Potassium Salt, (Z,Z)-Isomer Linoleic Acid, Sodium Salt, (E,E)-Isomer Linoleic Acid, Sodium Salt, (E,E)-Isomer Linoleic Acid, Sodium Salt, (Z,Z)-Isomer Linoleic Acid, Sodium Salt, (Z,Z)-Isomer Linoelaidic Acid, (E,Z)-Isomer Linoelaidic Acid, (E,Z)-Isomer Linoleic Acid, (Z,Z)-Isomer, 14C-Labeled Linoleic Acid, (Z,Z)-Isomer, 14C-Labeled

Below are MeSH descriptors whose meaning is more general than "Linoleic Acid".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Fatty Acids, Essential [D10.251.355.310]
Linoleic Acids [D10.251.355.310.515]
Linoleic Acid [D10.251.355.310.515.500]
Fatty Acids, Omega-6 [D10.251.355.343]
Linoleic Acids [D10.251.355.343.500]
Linoleic Acid [D10.251.355.343.500.500]

Below are MeSH descriptors whose meaning is related to "Linoleic Acid".

Below are MeSH descriptors whose meaning is more specific than "Linoleic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Linoleic Acid" by people in this website by year, and whether "Linoleic Acid" was a major or minor topic of these publications.

Bar chart showing 13 publications over 12 distinct years, with a maximum of 2 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2002	0	2	2
2004	1	0	1
2008	1	0	1
2009	0	1	1
2013	0	1	1
2015	0	1	1
2018	0	1	1
2020	1	0	1
2021	1	0	1
2023	1	0	1

Below are the most recent publications written about "Linoleic Acid" by people in Profiles.

Zhang J, Yang J, Duval C, Edin ML, Williams A, Lei L, Tu M, Pourmand E, Song R, Graves JP, DeGraff LM, Wong JJ, Wang Y, Sun Q, Sanidad KZ, Wong S, Han Y, Zhang Z, Lee KSS, Park Y, Xiao H, Liu Z, Decker EA, Cui W, Zeldin DC, Zhang G. CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 07; 37(7):e23009.

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Yao M, Kitamura F, Han Y, Du H, Julian McClements D, Xiao H. Adverse effects of linoleic acid: Influence of lipid oxidation on lymphatic transport of citrus flavonoid and enterocyte morphology. Food Chem. 2022 Feb 01; 369:130968.

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Xie M, Yang J, Zhang J, Sherman HL, Zhang Z, Minter LM, Hammock BD, Park Y, Zhang G. Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in Il-10-/- Mice. J Agric Food Chem. 2020 Jul 22; 68(29):7641-7647.

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Shen P, Kershaw JC, Yue Y, Wang O, Kim KH, McClements DJ, Park Y. Effects of conjugated linoleic acid (CLA) on fat accumulation, activity, and proteomics analysis in Caenorhabditis elegans. Food Chem. 2018 May 30; 249:193-201.

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Wu JHY, Marklund M, Imamura F, Tintle N, Ardisson Korat AV, de Goede J, Zhou X, Yang WS, de Oliveira Otto MC, Kr?ger J, Qureshi W, Virtanen JK, Bassett JK, Frazier-Wood AC, Lankinen M, Murphy RA, Rajaobelina K, Del Gobbo LC, Forouhi NG, Luben R, Khaw KT, Wareham N, Kalsbeek A, Veenstra J, Luo J, Hu FB, Lin HJ, Siscovick DS, Boeing H, Chen TA, Steffen B, Steffen LM, Hodge A, Eriksdottir G, Smith AV, Gudnason V, Harris TB, Brouwer IA, Berr C, Helmer C, Samieri C, Laakso M, Tsai MY, Giles GG, Nurmi T, Wagenknecht L, Schulze MB, Lemaitre RN, Chien KL, Soedamah-Muthu SS, Geleijnse JM, Sun Q, Harris WS, Lind L, ?rnl?v J, Riserus U, Micha R, Mozaffarian D. Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39?740 adults from 20 prospective cohort studies. Lancet Diabetes Endocrinol. 2017 12; 5(12):965-974.

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Gramlich L, Meddings L, Alberda C, Wichansawakun S, Robbins S, Driscoll D, Bistrian B. Essential Fatty Acid Deficiency in 2015: The Impact of Novel Intravenous Lipid Emulsions. JPEN J Parenter Enteral Nutr. 2015 Sep; 39(1 Suppl):61S-6S.

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Yang Y, McClements DJ. Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. J Colloid Interface Sci. 2013 Sep 01; 405:312-21.

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Burstein S, McQuain C, Salmonsen R, Seicol B. N-Amino acid linoleoyl conjugates: anti-inflammatory activities. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):872-5.

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Litvinov D, Selvarajan K, Garelnabi M, Brophy L, Parthasarathy S. Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. Atherosclerosis. 2010 Apr; 209(2):449-54.

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Garelnabi M, Selvarajan K, Litvinov D, Santanam N, Parthasarathy S. Dietary oxidized linoleic acid lowers triglycerides via APOA5/APOClll dependent mechanisms. Atherosclerosis. 2008 Aug; 199(2):304-9.

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