Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.
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Faust TE, Saito A, Ishikawa S, Yang K, Xin W, Namkung H, Agarwal A, Ramos A, Lee BJ, Hayes L, Srivastava R, Adelakun S, Saha S, Palen T, Cash-Padgett T, Wood DJ, Carloni E, Yusa R, Jaaro-Peled H, Fahey JW, Bergles DE, Ishizuka K, Sawa A. Astrocyte redox imbalance underlies prelimbic neuronal hypoactivity and maladaptive affective behaviors in epilepsy. Sci Adv. 2026 Jul 31; 12(31):eaef6777.
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Wan F, He J, Ma H, PiresFerreira D, Kumanan V, Lee JS, Chen X, He R, Su Q, Gallagher TL, Zhu S, Cabrera GT, Zhao L, Shen J, Gruntman A, Brown RH, Xu Z, Gao G, Xie J. Intravenous administration of an engineered AAV9-gene-silencing vector suppresses human SOD1 and extends survival in an ALS mouse model. Nat Commun. 2026 06 25; 17(1).
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Sagarbarria I, Seo J, Smith AJ, Vazey EM, Tremblay KD, Mager J, Hardy JA. Optimized detection of caspase-6 activation in a murine inflammation model to inform neurodegenerative disease therapies. PLoS One. 2026; 21(6):e0351312.
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Labadie BW, Obradovic A, Raufi AG, Wasko UN, Tomassoni L, Ge L, May M, Vij M, Li L, Ross I, Sedycius SS, Sender N, Dreher N, Wu L, Abuzaid S, Iuga A, Shah P, Wulfkuhle JD, Bates S, Wong W, Pellicciotta I, Lyashchenko AK, Safran H, Izar B, Petricoin EF, Cremers S, Tan AC, Lee S, Califano A, Olive KP, Manji GA. Targeting of MEK and Autophagy in Pancreatic Adenocarcinoma and Analysis of Treatment Sensitivity in Preclinical and Clinical Models: MEKiAUTO. JCO Precis Oncol. 2026 Jun; 10(6):e2600138.
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Suzuki M, Hasegawa Y, Zhang H, Liang Z, Tie G, Shivdasani RA, Waldor MK. IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice. Nat Microbiol. 2026 Jul; 11(7):1949-1966.
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Gallage S, Castro RE, Estall J, Tabas I, Anstee QM, Tiniakos DG, Szabo G, Yu J, Desdouets C, Tacke F, Oakley F, Heikenwalder M. EASL position paper on preclinical models of steatotic liver disease. J Hepatol. 2026 Aug; 85(2):345-382.
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Chen X, Xie Q, Nath SJ, Tang M, Ma H, G?nes Y?, Sharma T, Liu H, Cui M, Du A, Lu M, Liu SY, Wassamon B, Xu M, Wu JY, Su Q, Fitzgibbons TP, Liu J, Wan F, Kumanan V, He R, Ma Y, Yang J, Gray-Edwards HL, Gallagher TL, Tai PWL, Gao G, Xie J. Long-term comparative analysis of AAV9-mediated gene replacement therapies for spinal muscular atrophy in mice. Nat Commun. 2026 May 23; 17(1).
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Carbone E, Scibetta S, Cappella M, Crestini A, Perrone F, Hallulli M, Rosa P, Rivabene R, Maiolo F, Simonelli V, Ricceri L, Di Bari MA, De Luca G, Vanacore N, Lacorte E, Piscopo P. A systematic review on the effects of hypercaloric diet in animal models of Alzheimer's disease. J Alzheimers Dis. 2026 07; 112(2):576-610.
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Powell DA, Shubitz LF, Butkiewicz CD, Trinh HT, Georgieva T, Hsu AP, Ostroff GR, Holland SM, Frelinger JA, Galgiani JN. DECTIN-1 stalk length determines binding ability, immune response, and survival in a mouse model of coccidioidomycosis. J Immunol. 2026 May 14; 215(5).
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Wang J, Turgeon CT, Loken PR, Gray-Edwards H, Gao G, Tortorelli S, Wang D, Strauss KA. Systemic dual-gene therapy reverses biochemical intoxication in the central metabolic compartment of Bckdha-/- mice. Mol Ther. 2026 Aug 05; 34(8):4569-4580.