Disease Models, Animal

"Disease Models, Animal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Descriptor ID	D004195
MeSH Number(s)	C22.232 E05.598.500 E05.599.395.080
Concept/Terms	Disease Models, Animal Disease Models, Animal Animal Disease Model Animal Disease Models Disease Model, Animal

Below are MeSH descriptors whose meaning is more general than "Disease Models, Animal".

Diseases [C]
Animal Diseases [C22]
Disease Models, Animal [C22.232]
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Models, Animal [E05.598]
Disease Models, Animal [E05.598.500]
Models, Theoretical [E05.599]
Models, Biological [E05.599.395]
Disease Models, Animal [E05.599.395.080]

Below are MeSH descriptors whose meaning is related to "Disease Models, Animal".

Below are MeSH descriptors whose meaning is more specific than "Disease Models, Animal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Disease Models, Animal" by people in this website by year, and whether "Disease Models, Animal" was a major or minor topic of these publications.

Bar chart showing 1441 publications over 31 distinct years, with a maximum of 98 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	6	7
1996	0	3	3
1997	0	5	5
1998	0	3	3
1999	0	5	5
2000	2	10	12
2001	5	14	19
2002	3	27	30
2003	2	33	35
2004	7	41	48
2005	7	41	48
2006	5	47	52
2007	5	51	56
2008	9	45	54
2009	11	48	59
2010	13	42	55
2011	13	59	72
2012	9	45	54
2013	6	57	63
2014	11	72	83
2015	10	59	69
2016	7	91	98
2017	7	72	79
2018	5	89	94
2019	6	69	75
2020	9	70	79
2021	5	56	61
2022	0	27	27
2023	0	17	17
2024	17	37	54
2025	0	25	25

Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.

Lou S, DJiake Tihagam R, Wasko UN, Equbal Z, Venkatesan S, Braczyk K, Przanowski P, Il Koo B, Saltani I, Singh AT, Likhite S, Powers S, Souza GMPR, Maxwell RA, Yu J, Zhu LJ, Beenhakker M, Abbott SBG, Lu Z, Green MR, Meyer KC, Tushir-Singh J, Bhatnagar S. Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype. Nat Commun. 2025 Jul 04; 16(1):6169.

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Capps MES, Moyer AJ, Conklin CL, Martina V, Torija-Olson EG, Klein MC, Gannaway WC, Calhoun CCS, Vivian MD, Thyme SB. Disrupted diencephalon development and neuropeptidergic pathways in zebrafish with autism-risk mutations. Proc Natl Acad Sci U S A. 2025 Jun 10; 122(23):e2402557122.

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Ahmed M, Fischer S, Robert KL, Lange KI, Stuck MW, Best S, Johnson CA, Pazour GJ, Blacque OE, Nandadasa S. Cleavage of the Meckel-Gruber syndrome protein TMEM67 by ADAMTS9 uncouples Wnt signaling and ciliogenesis. Nat Commun. 2025 May 28; 16(1):4946.

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Ahn M, Dostal J, Hegde P, Lee DJ. CTLA-4 expression on tregs is needed for suppression of autoimmune uveitis. Sci Rep. 2025 May 22; 15(1):17745.

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Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.

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Castagnoli R, Pala F, Subramanian P, Oguz C, Schwarz B, Lim AI, Burns AS, Fontana E, Bosticardo M, Corsino C, Angelova A, Delmonte OM, Kenney H, Riley D, Smith G, Ott de Bruin L, Oikonomou V, Dos Santos Dias L, Fink D, Bohrnsen E, Kimzey CD, Marseglia GL, Alva-Lozada G, Bergerson JRE, Brett A, Brigatti KW, Dimitrova D, Dutmer CM, Freeman AF, Ale H, Holland SM, Licciardi F, Pasic S, Poskitt LE, Potts DE, Dasso JF, Sharapova SO, Strauss KA, Ward BR, Yilmaz M, Kuhns DB, Lionakis MS, Daley SR, Kong HH, Segre JA, Villa A, Pittaluga S, Walter JE, Vujkovic-Cvijin I, Belkaid Y, Notarangelo LD. Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency. J Exp Med. 2025 Aug 04; 222(8).

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Roger AL, El Haddad L, Huston ML, Kehoe S, Le D, Khan M, Scarrow E, Gonzalez T, Benkert A, Asokan A, ElMallah MK. GAA replacement improves respiratory muscle, neural, and alveolar pathology in the pompe mouse. Respir Physiol Neurobiol. 2025 07; 335:104433.

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Miller BR, Gonzaga-Jauregui C, Brigatti KW, de Jong J, Breese RS, Ko SY, Puffenberger EG, Van Hout C, Young M, Luna VM, Staples J, First MB, Gregoire HJ, Dwork AJ, Pefanis E, McCarthy S, Brydges S, Rojas J, Ye B, Stahl E, Di Gioia SA, Hen R, Elwood K, Rosoklija G, Li D, Mellis S, Carey D, Croll SD, Overton JD, Macdonald LE, Economides AN, Shuldiner AR, Chuhma N, Rayport S, Amin N, Kushner SA, Alessandri-Haber N, Markx S, Strauss KA. A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice. Proc Natl Acad Sci U S A. 2025 Apr 22; 122(16):e2404754122.

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Proulx MK, Wiggins CD, Reames CJ, Wu C, Kiritsy MC, Xu P, Gallant JC, Grace PS, Fenderson BA, Smith CM, Lindestam Arlehamn CS, Alter G, Lauffenburger DA, Sassetti CM. Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans. J Exp Med. 2025 Jul 07; 222(7).

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Gutmann DH, Boehm JS, Karlsson EK, Padron E, Seshadri M, Wallis D, Snyder JC. Precision preclinical modeling to advance cancer treatment. J Natl Cancer Inst. 2025 Apr 01; 117(4):586-594.

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