Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.
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Olde Heuvel F, Pagliarini M, Sun F, Lupu L, Zhao Z, Cui L, Zhang J, Halbgebauer R, Mannes M, Boeckers TM, Knöll B, Lien E, Mollnes TE, Huber-Lang M, Roselli F. Loss of C3 and CD14 reduces region-specific neuroinflammation in a murine polytrauma model. Inflamm Res. 2026 Sep 24; 75(1).
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Maguire AS, Ta NL, Gross AL, Garrett CJ, Zimmerman AD, Diffie EB, Osterhoudt DE, Pacer SH, Mitchell ML, Cannon JS, Hall PI, Sandey M, Cole RC, Seyfried TN, Gray-Edwards HL, Sena-Esteves M, Martin DR. Intravenous gene therapy improves life span and clinical outcomes in a feline model of Sandhoff disease. Sci Transl Med. 2026 09 09; 18(866):eadx2447.
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Boudi A, Sapp E, Li YY, Shing K, Kegel-Gleason K, Petrozziello T, Sadri-Vakili G, Aronin N, DiFiglia M, Li X. Early reduction of myelin-associated glycoprotein at myelin membranes in Huntington's disease. Exp Neurol. 2026 Dec; 406:115995.
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Belgrad J, Summers A, Landles C, Greene JR, Hildebrand S, Knox E, Sapp E, Yamada N, Furgal R, Miller R, Osborne GF, Chase K, Luu E, Freedman J, Bramato B, McHugh N, Nnah I, Benoit V, O'Reilly D, Greer P, Bates GP, Vogt TF, Lee R, Howland D, DiFiglia M, Aronin N, Khvorova A. Blocking somatic repeat expansion and lowering huntingtin by RNAi synergize to attenuate Huntington's disease pathogenesis in mice. Sci Transl Med. 2026 Aug 12; 18(862):eaea3104.
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Wang Y, Peng W, Fan W, Xiao H, Guo S, Tang Z, Qin J. Yakuchinone B Ameliorates DSS-Induced Colitis by Modulating the Gut Microbiota-Metabolite Axis. Nutrients. 2026 Aug 12; 18(16).
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Wayne CR, Akcan U, Faust TE, Durán-Laforet V, Jamoul D, Bremner L, Ampatey N, Akcan BT, Ho SJ, Ciric B, Delaney SL, Vargas WS, Swedo S, Menon V, Schafer DP, Cutforth T, Agalliu D. Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in a mouse model for post-streptococcal encephalitis. Nat Commun. 2026 Aug 11; 17(1).
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Batista AR, Scholand AC, Callahan WS, Watson MK, Sion CM, Mola T, O'Hara K, Wentworth SA, Sena-Esteves WS, King OD, King RM, Sena-Esteves M. AAV-mediated gene therapy demonstrates phenotypic rescue in a mouse model of Cockayne syndrome. J Clin Invest. 2026 Sep 15; 136(18).
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Faust TE, Saito A, Ishikawa S, Yang K, Xin W, Namkung H, Agarwal A, Ramos A, Lee BJ, Hayes L, Srivastava R, Adelakun S, Saha S, Palen T, Cash-Padgett T, Wood DJ, Carloni E, Yusa R, Jaaro-Peled H, Fahey JW, Bergles DE, Ishizuka K, Sawa A. Astrocyte redox imbalance underlies prelimbic neuronal hypoactivity and maladaptive affective behaviors in epilepsy. Sci Adv. 2026 Jul 31; 12(31):eaef6777.
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Messias SGDS, de Paula IÉS, Cardoso KF, Garcia CC, de Mendonça Ângelo ALP, de Faria Gonçalves AP, Melo EM, Tavares LP, Faustino LP, Alves PA, Dos Reis JGAC, Teixeira-Carvalho A, Antonelli LRDV, Xavier MAP, Martins-Filho OA, Machado AMV, Araújo MSS. Assessment of a recombinant influenza virus carrying interleukin 7 gene as a platform for novel immunotherapeutic approaches. Immunol Lett. 2026 Dec; 282:107223.
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Hariharan VN, Summers A, Clipperton-Allen AE, Caiazzi J, Hildebrand SR, O' Reilly D, Tang Q, Kennedy Z, Echeverria D, McHugh N, Cooper D, Sousa J, Ferguson C, Fakih HH, Bogdanik L, Coenraads M, Khvorova A. Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality in an MECP2 duplication mouse model. Nat Commun. 2026 Jul 21; 17(1).