 p38 Mitogen-Activated Protein Kinases
"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
| Descriptor ID |
D048051
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.878 D08.811.913.696.620.682.700.646.750.843 D12.644.360.450.835 D12.776.476.450.835
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| Concept/Terms |
p38 Mitogen-Activated Protein Kinases- p38 Mitogen-Activated Protein Kinases
- p38 Mitogen Activated Protein Kinases
- p38 SAPK
- p38 MAPK
- MAPK, p38
- p38 Protein Kinase
- Protein Kinase, p38
- Mitogen-Activated Protein Kinase p38
- Mitogen Activated Protein Kinase p38
- p38 MAP Kinase
- MAP Kinase, p38
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Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1998 | 0 | 2 | 2 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 9 | 9 | | 2003 | 0 | 9 | 9 | | 2004 | 2 | 7 | 9 | | 2005 | 3 | 6 | 9 | | 2006 | 2 | 3 | 5 | | 2007 | 2 | 6 | 8 | | 2008 | 1 | 1 | 2 | | 2009 | 3 | 5 | 8 | | 2010 | 1 | 1 | 2 | | 2011 | 4 | 3 | 7 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 2 | 3 | 5 | | 2015 | 0 | 2 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.
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Sindhava VJ, Oropallo MA, Moody K, Naradikian M, Higdon LE, Zhou L, Myles A, Green N, Nündel K, Stohl W, Schmidt AM, Cao W, Dorta-Estremera S, Kambayashi T, Marshak-Rothstein A, Cancro MP. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017 May 01; 127(5):1651-1663.
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Girnius N, Davis RJ. TNFa-Mediated Cytotoxic Responses to IAP Inhibition Are Limited by the p38a MAPK Pathway. Cancer Cell. 2016 Feb 08; 29(2):131-3.
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Cheesman HK, Feinbaum RL, Thekkiniath J, Dowen RH, Conery AL, Pukkila-Worley R. Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans. G3 (Bethesda). 2016 Jan 27; 6(3):541-9.
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Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM, Thorpe CM. Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. Infect Immun. 2015 Oct 19; 84(1):138-48.
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Ding W, Smulan LJ, Hou NS, Taubert S, Watts JL, Walker AK. s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways. Cell Metab. 2015 Oct 06; 22(4):633-45.
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Ren Z, Ambros VR. Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress. Proc Natl Acad Sci U S A. 2015 May 5; 112(18):E2366-75.
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Hartwell HJ, Petrosky KY, Fox JG, Horseman ND, Rogers AB. Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31):11455-60.
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Mitchell MJ, Lin KS, King MR. Fluid shear stress increases neutrophil activation via platelet-activating factor. Biophys J. 2014 May 20; 106(10):2243-53.
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Zaidi SK, Shen WJ, Bittner S, Bittner A, McLean MP, Han J, Davis RJ, Kraemer FB, Azhar S. p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene. J Mol Endocrinol. 2014 Aug; 53(1):1-16.
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Maimon A, Mogilevsky M, Shilo A, Golan-Gerstl R, Obiedat A, Ben-Hur V, Lebenthal-Loinger I, Stein I, Reich R, Beenstock J, Zehorai E, Andersen CL, Thorsen K, Orntoft TF, Davis RJ, Davidson B, Mu D, Karni R. Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation. Cell Rep. 2014 Apr 24; 7(2):501-13.
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