 Myosins
"Myosins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
| Descriptor ID |
D009218
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| MeSH Number(s) |
D05.750.078.730.475 D08.811.277.040.025.193.750 D12.776.210.500.600 D12.776.220.525.475
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| Concept/Terms |
Myosins- Myosins
- Adenosine Triphosphatase, Myosin
- Myosin Adenosine Triphosphatase
- Adenosinetriphosphatase, Myosin
- Myosin ATPase
- ATPase, Myosin
- Myosin
- Myosin Adenosinetriphosphatase
- Actin-Activated ATPase
- Actin Activated ATPase
- ATPase, Actin-Activated
- ATPase, Actin Activated
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Below are MeSH descriptors whose meaning is more general than "Myosins".
Below are MeSH descriptors whose meaning is more specific than "Myosins".
This graph shows the total number of publications written about "Myosins" by people in this website by year, and whether "Myosins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1987 | 1 | 0 | 1 | | 1989 | 2 | 1 | 3 | | 1990 | 1 | 0 | 1 | | 1991 | 3 | 0 | 3 | | 1992 | 2 | 1 | 3 | | 1993 | 1 | 1 | 2 | | 1994 | 2 | 1 | 3 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 4 | 1 | 5 | | 2002 | 3 | 0 | 3 | | 2003 | 1 | 3 | 4 | | 2004 | 3 | 1 | 4 | | 2005 | 2 | 0 | 2 | | 2006 | 3 | 1 | 4 | | 2008 | 7 | 1 | 8 | | 2009 | 1 | 2 | 3 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 2 | 3 | | 2015 | 4 | 2 | 6 | | 2016 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myosins" by people in Profiles.
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Irving TC, Craig R. Getting into the thick (and thin) of it. J Gen Physiol. 2019 May 06; 151(5):610-613.
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Orme MH, Liccardi G, Moderau N, Feltham R, Wicky-John S, Tenev T, Aram L, Wilson R, Bianchi K, Morris O, Monteiro Domingues C, Robertson D, Tare M, Wepf A, Williams D, Bergmann A, Gstaiger M, Arama E, Ribeiro PS, Meier P. The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nat Commun. 2016 Mar 10; 7:10972.
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Yang S, Woodhead JL, Zhao FQ, Sulbarán G, Craig R. An approach to improve the resolution of helical filaments with a large axial rise and flexible subunits. J Struct Biol. 2016 Jan; 193(1):45-54.
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Esteves da Silva M, Adrian M, Schätzle P, Lipka J, Watanabe T, Cho S, Futai K, Wierenga CJ, Kapitein LC, Hoogenraad CC. Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture. Cell Rep. 2015 Nov 3; 13(5):933-43.
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Sulbarán G, Alamo L, Pinto A, Márquez G, Méndez F, Padrón R, Craig R. An invertebrate smooth muscle with striated muscle myosin filaments. Proc Natl Acad Sci U S A. 2015 Oct 20; 112(42):E5660-8.
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Woodhead JL, Craig R. Through Thick and Thin--Interfilament Communication in Muscle. Biophys J. 2015 Aug 18; 109(4):665-7.
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Debold EP. Biological machines: Molecular motor teamwork. Nat Nanotechnol. 2015 Aug; 10(8):656-7.
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Baskin TI. Upward organelle motility. J Integr Plant Biol. 2015 Jan; 57(1):2-3.
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Swenson AM, Trivedi DV, Rauscher AA, Wang Y, Takagi Y, Palmer BM, Málnási-Csizmadia A, Debold EP, Yengo CM. Magnesium modulates actin binding and ADP release in myosin motors. J Biol Chem. 2014 Aug 22; 289(34):23977-91.
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Lucas B, Ammar T, Khogali S, DeJong D, Barbalinardo M, Nishi C, Hayward LJ, Renaud JM. Contractile abnormalities of mouse muscles expressing hyperkalemic periodic paralysis mutant NaV1.4 channels do not correlate with Na+ influx or channel content. Physiol Genomics. 2014 Jun 1; 46(11):385-97.
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