A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling.
Lin L, Chamberlain L, Pak ML, Nagarajan A, Gupta R, Zhu LJ, Wright CM, Fong KM, Wajapeyee N, Green MR. A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling. Cancer Discov. 2014 Oct; 4(10):1168-81.
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Adaptor Proteins, Signal Transducing
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Animals
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Carcinoma, Squamous Cell
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Cell Line, Tumor
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Cell Transformation, Neoplastic
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Disease Models, Animal
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DNA Methylation
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Drug Resistance, Neoplasm
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Gene Expression Regulation, Neoplastic
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Gene Knockdown Techniques
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Heterografts
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Humans
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Lung Neoplasms
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Mice
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Promoter Regions, Genetic
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Protein Binding
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Receptor, Fibroblast Growth Factor, Type 1
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RNA Interference
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RNA, Small Interfering
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Signal Transduction
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Tumor Suppressor Proteins