Hepatocyte Nuclear Factor 1
"Hepatocyte Nuclear Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor and homeodomain protein that regulates the expression of a large set of hepatic proteins including SERUM ALBUMIN; beta-fibrinogen; and ALPHA 1-ANTITRYPSIN. It is composed of hetero- or homo-dimers of HEPATOCYTE NUCLEAR FACTOR 1-ALPHA and HEPATOCYTE NUCLEAR FACTOR 1-BETA.
| Descriptor ID |
D051537
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| MeSH Number(s) |
D12.776.260.262.500 D12.776.260.400.218 D12.776.660.352.500 D12.776.930.318.500
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1- Hepatocyte Nuclear Factor 1
- Hepatic Nuclear Factor 1
- HNF-1 Protein
- HNF 1 Protein
- HNF1 Transcription Factor
- Transcription Factor, HNF1
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1" was a major or minor topic of these publications.
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1" by people in Profiles.
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Bach I, Yaniv M. More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing. EMBO J. 1993 Nov; 12(11):4229-42.
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Bach I, Pontoglio M, Yaniv M. Structure of the gene encoding hepatocyte nuclear factor 1 (HNF1). Nucleic Acids Res. 1992 Aug 25; 20(16):4199-204.
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Bach I, Mattei MG, Cereghini S, Yaniv M. Two members of an HNF1 homeoprotein family are expressed in human liver. Nucleic Acids Res. 1991 Jul 11; 19(13):3553-9.
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Chouard T, Blumenfeld M, Bach I, Vandekerckhove J, Cereghini S, Yaniv M. A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain. Nucleic Acids Res. 1990 Oct 11; 18(19):5853-63.
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Bach I, Galcheva-Gargova Z, Mattei MG, Simon-Chazottes D, Gu?net JL, Cereghini S, Yaniv M. Cloning of human hepatic nuclear factor 1 (HNF1) and chromosomal localization of its gene in man and mouse. Genomics. 1990 Sep; 8(1):155-64.