"Smad4 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.
| Descriptor ID |
D051901
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| MeSH Number(s) |
D12.644.360.024.334.750 D12.776.157.057.170.750 D12.776.260.713.750 D12.776.476.024.428.750 D12.776.624.776.760 D12.776.930.806.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Smad4 Protein".
Below are MeSH descriptors whose meaning is more specific than "Smad4 Protein".
This graph shows the total number of publications written about "Smad4 Protein" by people in this website by year, and whether "Smad4 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smad4 Protein" by people in Profiles.
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Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019 Apr 16; 27(3):708-718.e10.
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Fan J, Yang MX, Ouyang Q, Fu D, Xu Z, Liu X, Mino-Kenudson M, Geng J, Tang F. Phosphatase PPM1A is a novel prognostic marker in pancreatic ductal adenocarcinoma. Hum Pathol. 2016 09; 55:151-8.
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Mimori K, Yamashita K, Ohta M, Yoshinaga K, Ishikawa K, Ishii H, Utsunomiya T, Barnard GF, Inoue H, Mori M. Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells. Clin Cancer Res. 2004 Dec 15; 10(24):8243-9.