Oligonucleotides, Antisense

"Oligonucleotides, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.

Descriptor ID	D016376
MeSH Number(s)	D13.150.480 D13.444.600.150.640 D13.695.578.424.480 D27.720.470.530.600.150.640
Concept/Terms	Oligonucleotides, Antisense Oligonucleotides, Antisense Antisense Oligonucleotides Anti-Sense Oligonucleotides Anti Sense Oligonucleotides Oligonucleotides, Anti-Sense

Below are MeSH descriptors whose meaning is more general than "Oligonucleotides, Antisense".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Antisense Elements (Genetics) [D13.150]
Oligonucleotides, Antisense [D13.150.480]
Nucleic Acids [D13.444]
Nucleic Acid Probes [D13.444.600]
Antisense Elements (Genetics) [D13.444.600.150]
Oligonucleotides, Antisense [D13.444.600.150.640]
Nucleotides [D13.695]
Polynucleotides [D13.695.578]
Oligonucleotides [D13.695.578.424]
Oligonucleotides, Antisense [D13.695.578.424.480]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Laboratory Chemicals [D27.720.470]
Molecular Probes [D27.720.470.530]
Nucleic Acid Probes [D27.720.470.530.600]
Antisense Elements (Genetics) [D27.720.470.530.600.150]
Oligonucleotides, Antisense [D27.720.470.530.600.150.640]

Below are MeSH descriptors whose meaning is related to "Oligonucleotides, Antisense".

Below are MeSH descriptors whose meaning is more specific than "Oligonucleotides, Antisense".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Oligonucleotides, Antisense" by people in this website by year, and whether "Oligonucleotides, Antisense" was a major or minor topic of these publications.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
2002	0	1	1
2003	0	1	1
2006	0	2	2
2014	0	1	1
2018	0	1	1
2022	1	0	1

Below are the most recent publications written about "Oligonucleotides, Antisense" by people in Profiles.

Wang F, Calvo-Roitberg E, Rembetsy-Brown JM, Fang M, Sousa J, Kartje ZJ, Krishnamurthy PM, Lee J, Green MR, Pai AA, Watts JK. G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects. Nucleic Acids Res. 2022 12 09; 50(22):12657-12673.

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Shin M, Chan IL, Cao Y, Gruntman AM, Lee J, Sousa J, Rodr?guez TC, Echeverria D, Devi G, Debacker AJ, Moazami MP, Krishnamurthy PM, Rembetsy-Brown JM, Kelly K, Yukselen O, Donnard E, Parsons TJ, Khvorova A, Sontheimer EJ, Maehr R, Garber M, Watts JK. Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts. Nucleic Acids Res. 2022 08 26; 50(15):8418-8430.

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Shin M, Meda Krishnamurthy P, Devi G, Watts JK. Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction. Nucleic Acid Ther. 2022 02; 32(1):66-73.

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Didiot MC, Ferguson CM, Ly S, Coles AH, Smith AO, Bicknell AA, Hall LM, Sapp E, Echeverria D, Pai AA, DiFiglia M, Moore MJ, Hayward LJ, Aronin N, Khvorova A. Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin. Cell Rep. 2018 09 04; 24(10):2553-2560.e5.

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Nagarajan A, Petersen MC, Nasiri AR, Butrico G, Fung A, Ruan HB, Kursawe R, Caprio S, Thibodeau J, Bourgeois-Daigneault MC, Sun L, Gao G, Bhanot S, Jurczak MJ, Green MR, Shulman GI, Wajapeyee N. MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels. Nat Commun. 2016 08 31; 7:12639.

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Chen L, Cheng D, Liu G, Dou S, Wang Y, Liu X, Liu Y, Rusckowski M. Detection of Klebsiella. Pneumoniae Infection with an Antisense Oligomer Against its Ribosomal RNA. Mol Imaging Biol. 2016 08; 18(4):527-34.

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Toh ZY, Thandar Aung-Htut M, Pinniger G, Adams AM, Krishnaswarmy S, Wong BL, Fletcher S, Wilton SD. Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS One. 2016; 11(1):e0145620.

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Wang D, Gao G. State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications. Discov Med. 2014 Sep; 18(98):151-61.

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Baigude H, Li Z, Zhou Y, Rana TM. miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets. Angew Chem Int Ed Engl. 2012 Jun 11; 51(24):5880-3.

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Szabo G, Sarnow P, Bala S. MicroRNA silencing and the development of novel therapies for liver disease. J Hepatol. 2012 Aug; 57(2):462-6.

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