"Pyrimidine Dimers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION.
| Descriptor ID |
D011740
|
| MeSH Number(s) |
D03.383.742.686.600 D13.695.578.424.600 D13.695.740.600
|
| Concept/Terms |
Pyrimidine Dimers- Pyrimidine Dimers
- Dimers, Pyrimidine
- Cyclobutane-Pyrimidine Dimers
- Cyclobutane Pyrimidine Dimers
- Dimers, Cyclobutane-Pyrimidine
Thymine-Cyclobutane Dimer- Thymine-Cyclobutane Dimer
- Dimer, Thymine-Cyclobutane
- Thymine Cyclobutane Dimer
- Thymine-Thymine Cyclobutane Dimer
- Cyclobutane Dimer, Thymine-Thymine
- Dimer, Thymine-Thymine Cyclobutane
- Thymine Thymine Cyclobutane Dimer
- Thymine Dimers
- Dimers, Thymine
|
Below are MeSH descriptors whose meaning is more general than "Pyrimidine Dimers".
Below are MeSH descriptors whose meaning is more specific than "Pyrimidine Dimers".
This graph shows the total number of publications written about "Pyrimidine Dimers" by people in this website by year, and whether "Pyrimidine Dimers" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrimidine Dimers" by people in Profiles.
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Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010 Feb 04; 9(2):109-19.
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Adair JE, Maloney SC, Dement GA, Wertzler KJ, Smerdon MJ, Reeves R. High-mobility group A1 proteins inhibit expression of nucleotide excision repair factor xeroderma pigmentosum group A. Cancer Res. 2007 Jul 01; 67(13):6044-52.
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Adair JE, Kwon Y, Dement GA, Smerdon MJ, Reeves R. Inhibition of nucleotide excision repair by high mobility group protein HMGA1. J Biol Chem. 2005 Sep 16; 280(37):32184-92.