 Free Radicals
"Free Radicals" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
| Descriptor ID |
D005609
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| MeSH Number(s) |
D01.339 D02.389
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Free Radicals".
Below are MeSH descriptors whose meaning is more specific than "Free Radicals".
This graph shows the total number of publications written about "Free Radicals" by people in this website by year, and whether "Free Radicals" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 3 | 3 | | 2004 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Free Radicals" by people in Profiles.
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Viglianisi C, Di Pilla V, Menichetti S, Rotello VM, Candiani G, Malloggi C, Amorati R. Linking an a-tocopherol derivative to cobalt(0) nanomagnets: magnetically responsive antioxidants with superior radical trapping activity and reduced cytotoxicity. Chemistry. 2014 Jun 2; 20(23):6857-60.
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Park J, Yan M. Covalent functionalization of graphene with reactive intermediates. Acc Chem Res. 2013 Jan 15; 46(1):181-9.
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Kellett A, Howe O, O'Connor M, McCann M, Creaven BS, McClean S, Foltyn-Arfa Kia A, Casey A, Devereux M. Radical-induced DNA damage by cytotoxic square-planar copper(II) complexes incorporating o-phthalate and 1,10-phenanthroline or 2,2'-dipyridyl. Free Radic Biol Med. 2012 Aug 1; 53(3):564-76.
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Chen X, McRae S, Parelkar S, Emrick T. Polymeric phosphorylcholine-camptothecin conjugates prepared by controlled free radical polymerization and click chemistry. Bioconjug Chem. 2009 Dec; 20(12):2331-41.
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Ravi D, Muniyappa H, Das KC. Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells. J Biol Chem. 2005 Dec 2; 280(48):40084-96.
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Johnson MD, Yu LR, Conrads TP, Kinoshita Y, Uo T, Matthews JD, Lee SW, Smith RD, Veenstra TD, Morrison RS. Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry. J Biol Chem. 2004 Jun 18; 279(25):26685-97.
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Wettasinghe M, Bolling B, Plhak L, Xiao H, Parkin K. Phase II enzyme-inducing and antioxidant activities of beetroot (Beta vulgaris L.) extracts from phenotypes of different pigmentation. J Agric Food Chem. 2002 Nov 6; 50(23):6704-9.
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Bates B, Hirt L, Thomas SS, Akbarian S, Le D, Amin-Hanjani S, Whalen M, Jaenisch R, Moskowitz MA. Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals. Neurobiol Dis. 2002 Feb; 9(1):24-37.
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Kim D, Chung J. Akt: versatile mediator of cell survival and beyond. J Biochem Mol Biol. 2002 Jan 31; 35(1):106-15.
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Mancuso JR, McClements DJ, Decker EA. Iron-accelerated cumene hydroperoxide decomposition in hexadecane and trilaurin emulsions. J Agric Food Chem. 2000 Feb; 48(2):213-9.
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